Oxalobacter formigenes–derived bioactive factors stimulate oxalate transport by intestinal epithelial cells

D Arvans, YC Jung, D Antonopoulos… - Journal of the …, 2017 - journals.lww.com
Hyperoxaluria is a major risk factor for kidney stones and has no specific therapy, although
Oxalobacter formigenes colonization is associated with reduced stone risk. O. formigenes …

Aspalathus linearis (Rooibos) and Agmatine May Act Synergistically to Beneficially Modulate Intestinal Tight Junction Integrity and Inflammatory Profile

L Pretorius, C Smith - Pharmaceuticals, 2022 - mdpi.com
In order to promote gastrointestinal health, significant increases in the prevalence of
gastrointestinal disorders should be paralleled by similar surges in therapeutics research …

Arsenic exposure causes epigenetic dysregulation of IL-8 expression leading to proneoplastic changes in kidney cells

RD Singh, R Tiwari, H Khan, A Kumar, V Srivastava - Toxicology letters, 2015 - Elsevier
Prolonged arsenic exposure has been shown to cause several detrimental effects in adults.
However its effects following prenatal exposure are not well defined at the epigenetic level …

[HTML][HTML] NFAT1 promotes intratumoral neutrophil infiltration by regulating IL8 expression in breast cancer

A Kaunisto, WS Henry, L Montaser-Kouhsari… - Molecular …, 2015 - Elsevier
NFAT transcription factors are key regulators of gene expression in immune cells. In
addition, NFAT1-induced genes play diverse roles in mediating the progression of various …

Membrane lipid composition of bronchial epithelial cells influences antiviral responses during rhinovirus infection

MH Panchal, EJ Swindle, TJ Pell, WC Rowan… - Tissue …, 2024 - Taylor & Francis
Lipids and their mediators have important regulatory functions in many cellular processes,
including the innate antiviral response. The aim of this study was to compare the lipid …

[引用][C] The prostanoid EP4 receptor and its signaling pathway

U Yokoyama, K Iwatsubo, M Umemura, T Fujita… - Pharmacological …, 2013 - ASPET

Mice lacking prostaglandin E receptor subtype 4 manifest disrupted lipid metabolism attributable to impaired triglyceride clearance

Y Cai, F Ying, E Song, Y Wang, A Xu… - The FASEB …, 2015 - Wiley Online Library
Upon high‐fat feeding, prostaglandin E receptor subtype 4 (EP4)‐knockout mice gain less
body weight than their EP4+/+ littermates. We investigated the cause of the lean phenotype …

Lymphocytic colitis is associated with increased pro-inflammatory cytokine profile and up regulation of prostaglandin receptor EP4

I Dey, PL Beck, K Chadee - PLoS One, 2013 - journals.plos.org
Microscopic colitis (MC) is comprised of two entities, lymphocytic (LC) and collagenous
colitis. Up to 20% of patients with chronic diarrhea that have a normal appearing …

Extracellular nucleotides inhibit oxalate transport by human intestinal Caco-2-BBe cells through PKC-δ activation

R Amin, S Sharma, S Ratakonda… - American Journal of …, 2013 - journals.physiology.org
Nephrolithiasis remains a major health problem in Western countries. Seventy to 80% of
kidney stones are composed of calcium oxalate, and small changes in urinary oxalate affect …

PTGER2 activation induces PTGS-2 and growth factor gene expression in endometrial epithelial cells of cattle

L Gao, B Liu, W Mao, R Gao, S Zhang, C Fu… - Animal reproduction …, 2017 - Elsevier
The prostaglandin E 2 receptor 2 (PTGER2) is present in the endometrium and its gene
expression is accompanied with endometrial growth, however, it is unknown whether there …