HGF/c-MET pathway in cancer: from molecular characterization to clinical evidence
J Fu, X Su, Z Li, L Deng, X Liu, X Feng, J Peng - Oncogene, 2021 - nature.com
This review provides a comprehensive landscape of HGF/c-MET (hepatocyte growth factor
(HGF)/mesenchymal–epithelial transition factor (c-MET)) signaling pathway in cancers. First …
(HGF)/mesenchymal–epithelial transition factor (c-MET)) signaling pathway in cancers. First …
Receptors for respiratory syncytial virus infection and host factors regulating the life cycle of respiratory syncytial virus
Z Feng, L Xu, Z Xie - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections and
responsible for a large proportion of mortality in children and the elderly. There are no …
responsible for a large proportion of mortality in children and the elderly. There are no …
Interferon-induced protein 44 and interferon-induced protein 44-like restrict replication of respiratory syncytial virus
DC Busse, D Habgood-Coote, S Clare… - Journal of …, 2020 - Am Soc Microbiol
Cellular intrinsic immunity, mediated by the expression of an array of interferon-stimulated
antiviral genes, is a vital part of host defense. We have previously used a bioinformatic …
antiviral genes, is a vital part of host defense. We have previously used a bioinformatic …
Norovirus replication in human intestinal epithelial cells is restricted by the interferon-induced JAK/STAT signaling pathway and RNA polymerase II-mediated …
M Hosmillo, Y Chaudhry, K Nayak, F Sorgeloos… - MBio, 2020 - Am Soc Microbiol
Human noroviruses (HuNoV) are a leading cause of viral gastroenteritis worldwide and a
significant cause of morbidity and mortality in all age groups. The recent finding that HuNoV …
significant cause of morbidity and mortality in all age groups. The recent finding that HuNoV …
[HTML][HTML] Dissection of an impact of VDR and RXRA on the genomic activity of 1, 25 (OH) 2D3 in A431 squamous cell carcinoma
AM Olszewska, JI Nowak, K Myszczynski… - Molecular and Cellular …, 2024 - Elsevier
Background Human skin is the natural source, place of metabolism, and target for vitamin D
3. The classical active form of vitamin D 3, 1, 25 (OH) 2 D 3, expresses pluripotent properties …
3. The classical active form of vitamin D 3, 1, 25 (OH) 2 D 3, expresses pluripotent properties …
[HTML][HTML] CADM1 inhibits ovarian cancer cell proliferation and migration by potentially regulating the PI3K/Akt/mTOR pathway
X Si, F Xu, F Xu, M Wei, Y Ge, S Chenge - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Previous studies have shown that cell adhesion molecule 1 (CADM1), an immunoglobulin
superfamily member, is frequently inactivated but functions as a tumor suppressor in many …
superfamily member, is frequently inactivated but functions as a tumor suppressor in many …
Dual LSD1 and HDAC6 inhibition induces doxorubicin sensitivity in acute myeloid leukemia cells
Simple Summary GSK2879552 is a LSD1 inhibitor in clinical development. By structural
modification, we obtained an analogue that is a potent and selective dual inhibitor of HDAC6 …
modification, we obtained an analogue that is a potent and selective dual inhibitor of HDAC6 …
[HTML][HTML] CYP1A2 suppresses hepatocellular carcinoma through antagonizing HGF/MET signaling
Abstract Rationale: Hyperactivation of HGF/MET signaling pathway is a critical driver in liver
tumorigenesis. Cytochrome P450 1A2 (CYP1A2) was significantly down-regulated in …
tumorigenesis. Cytochrome P450 1A2 (CYP1A2) was significantly down-regulated in …
Identification of latent biomarkers in connection with progression and prognosis in oral cancer by comprehensive bioinformatics analysis
A Reyimu, Y Chen, X Song, W Zhou, J Dai… - World Journal of Surgical …, 2021 - Springer
Background Oral cancer (OC) is a common and dangerous malignant tumor with a low
survival rate. However, the micro level mechanism has not been explained in detail …
survival rate. However, the micro level mechanism has not been explained in detail …
IFI44L as a forward regulator enhancing host antituberculosis responses
H Jiang, L Tsang, H Wang, C Liu - Journal of Immunology …, 2021 - Wiley Online Library
Interferon‐induced protein 44‐like (IFI44L) gene is a type I interferon‐stimulated gene (ISG)
that plays a critical role in antiviral activity and constitutes a promising diagnostic marker …
that plays a critical role in antiviral activity and constitutes a promising diagnostic marker …