Obstructive sleep apnea, depression and cognitive impairment

J Vanek, J Prasko, S Genzor, M Ociskova, K Kantor… - Sleep medicine, 2020 - Elsevier
Objective Obstructive sleep apnea (OSA) is a severe disorder with a high prevalence.
Psychiatric comorbidities, especially depressive symptoms and cognitive dysfunction, are …

Connections between sleep and cognition in older adults

K Yaffe, CM Falvey, T Hoang - The Lancet Neurology, 2014 - thelancet.com
Sleep disturbances and cognitive impairment are common in older adults. Mounting
evidence points to a potential connection between sleep and cognitive function. Findings …

Sleep-disordered breathing advances cognitive decline in the elderly

RS Osorio, T Gumb, E Pirraglia, AW Varga, S Lu, J Lim… - Neurology, 2015 - AAN Enterprises
Objective: To examine whether the presence of sleep-disordered breathing (SDB) is
associated with an earlier age at mild cognitive impairment (MCI) or Alzheimer disease (AD) …

Sleep and Alzheimer's disease

L Peter-Derex, P Yammine, H Bastuji, B Croisile - Sleep medicine reviews, 2015 - Elsevier
Sleep disorders are frequent in Alzheimer's disease (AD), with a significant impact on
patients and caregivers and a major risk factor for early institutionalization. Micro …

Sleep and cognition in older adults

JM Dzierzewski, N Dautovich… - Sleep medicine clinics, 2018 - sleep.theclinics.com
This article reviews the growing literature examining sleep and cognitive functioning in older
adults. The main focus is on normal, age-related cognitive changes, as opposed to …

Sleep-disordered breathing and the risk of Alzheimer's disease

C Liguori, M Maestri, M Spanetta, F Placidi… - Sleep Medicine …, 2021 - Elsevier
Sleep-disordered breathing is highly prevalent in the elderly population. Obstructive sleep
apnea (OSA) represents the most common sleep disorder among the adult and elderly …

Modification of the relationship of the apolipoprotein E ε4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep

ASP Lim, L Yu, M Kowgier, JA Schneider… - JAMA …, 2013 - jamanetwork.com
Importance The apolipoprotein E (APOE [GenBank, 348; OMIM, 107741]) ε4 allele is a
common and well-established genetic risk factor for Alzheimer disease (AD). Sleep …

APOE genotype and Alzheimer's disease: the influence of lifestyle and environmental factors

E Angelopoulou, YN Paudel… - ACS chemical …, 2021 - ACS Publications
Alzheimer's disease (AD) is the most common neurodegenerative disorder with obscure
pathogenesis and no disease-modifying therapy to date. AD is multifactorial disease that …

Sleep characteristics and risk of dementia and Alzheimer's disease: the atherosclerosis risk in communities study

PL Lutsey, JR Misialek, TH Mosley, RF Gottesman… - Alzheimer's & …, 2018 - Elsevier
Introduction This study tested the hypotheses that late-midlife obstructive sleep apnea (OSA)
and short and long sleep duration are associated with dementia over 15 years of follow-up …

A combined neuropsychological and brain imaging study of obstructive sleep apnea

K Yaouhi, F Bertran, P Clochon… - Journal of sleep …, 2009 - Wiley Online Library
Patients with obstructive sleep apnea (OSA) show neuropsychological impairments ranging
from vigilance decrements, attentional lapses and memory gaps to decreased motor …