Postnatal growth and development of the human body and its specific organs are regulated
by a complex network of local and systemic factors which is poorly understood. This review …

Accurate measurement of height and weight using standardized techniques is a
fundamental component of pediatric medical visits. Calculation of height velocity over time …

Diagnosis of Growth Hormone Deficiency in Children and Adults | Endocrine Reviews | Oxford
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We have constructed a reference model to facilitate comparison of serum IGF-I values
among children, and thereby to improve the value of IGF-I measurements for diagnosis. The …

Background: Traditionally, measurement of plasma IGF-I and more recently of IGFBP-3 are
used to distinguish GHD from idiopathic short stature in slowly growing children, using a …

The insulin-like growth factors (IGF) and their binding proteins (IGFBP) have a wide variety
of physiological actions that are still being revealed. Both IGF and IGFBP have effects that …

Since human pituitary growth hormone (GH) became available for treatment in 1960,
followed in 1985 by recombinant human GH (rhGH), the diagnosis of GH deficiency (GHD) …

Until the advent of modern neuroradiological imaging techniques in 1989, a diagnosis of GH
deficiency in adults carried little significance other than as a marker of hypothalamo-pituitary …

OBJECTIVE Growth hormone status was assessed in a cohort of 32 (16 male) adults who
had received cranial irradiation (XRT) in childhood as part of their treatment for acute …

Growth hormone (GH) deficiency is a common pituitary hormone deficiency in childhood
cancer survivors (CCS). The identification, diagnosis, and treatment of those individuals at …