[HTML][HTML] Hyaluronan and reactive oxygen species signaling—novel cues from the matrix?

A Berdiaki, M Neagu, I Spyridaki, A Kuskov, S Perez… - Antioxidants, 2023 - mdpi.com
Hyaluronan (HA) is a naturally occurring non-sulfated glycosaminoglycan (GAG) localized to
the cell surface and the tissue extracellular matrix (ECM). It is composed of disaccharides …

[HTML][HTML] Hyaluronic acid: known for almost a century, but still in vogue

A Lierova, J Kasparova, A Filipova, J Cizkova… - Pharmaceutics, 2022 - mdpi.com
Hyaluronic acid (HA) has a special position among glycosaminoglycans. As a major
component of the extracellular matrix (ECM). This simple, unbranched polysaccharide is …

Development, characterization and sterilisation of Nanocellulose-alginate-(hyaluronic acid)-bioinks and 3D bioprinted scaffolds for tissue engineering

M Lafuente-Merchan, S Ruiz-Alonso… - Materials Science and …, 2021 - Elsevier
Abstract 3D-bioprinting is an emerging technology of high potential in tissue engineering
(TE), since it shows effective control over scaffold fabrication and cell distribution …

[HTML][HTML] Oxidative damage to hyaluronan–CD44 interactions as an underlying mechanism of action of oxidative stress-inducing cancer therapy

M Yusupov, A Privat-Maldonado, RM Cordeiro… - Redox biology, 2021 - Elsevier
Multiple cancer therapies nowadays rely on oxidative stress to damage cancer cells. Here
we investigated the biological and molecular effect of oxidative stress on the interaction …

[HTML][HTML] Absorbable hydrogel spacer use in prostate radiotherapy: a comprehensive review of phase 3 clinical trial published data

LI Karsh, ET Gross, CM Pieczonka, PJ Aliotta… - Urology, 2018 - Elsevier
Objective To provide an update on SpaceOAR System, a Food and Drug Administration–
approved hydrogel indicated to create distance between the prostate and the rectum which …

Nanocomposite of cosubstituted carbonated hydroxyapatite fabricated inside Poly (sodium hyaluronate-acrylamide) hydrogel template prepared by gamma radiation …

MM Ghobashy, NM El-Sawy, AS Kodous - Radiation Physics and Chemistry, 2021 - Elsevier
Carbonated hydroxyapatite (CCaHAp) closely mimics the chemical composition of apatite
found in human bone, compared to hydroxyapatite (HA). The present study aimed to prepare …

A multi-institutional clinical trial of rectal dose reduction via injected polyethylene-glycol hydrogel during intensity modulated radiation therapy for prostate cancer …

DY Song, KK Herfarth, M Uhl, MJ Eble… - International Journal of …, 2013 - Elsevier
Purpose To characterize the effect of a prostate-rectum spacer on dose to rectum during
external beam radiation therapy for prostate cancer and to assess for factors correlated with …

Hyaluronan and hyaluronan fragments

MK Cowman - Advances in carbohydrate chemistry and biochemistry, 2017 - Elsevier
The glycosaminoglycan hyaluronan (HA) is a key component of the microenvironment
surrounding cells. In healthy tissues, HA molecules have extremely high molecular mass …

Application technique: placement of a prostate–rectum spacer in men undergoing prostate radiation therapy

G Hatiboglu, M Pinkawa, JP Vallée… - BJU …, 2012 - Wiley Online Library
Study Type–Therapy (case series) Level of Evidence 4 What's known on the subject? and
What does the study add? Different spacing agents have been tested to reduce incidential …

Human collagen injections to reduce rectal dose during radiotherapy

WR Noyes, CC Hosford, SE Schultz - International Journal of Radiation …, 2012 - Elsevier
OBJECTIVES: The continuing search for interventions, which address the incidence and
grade of rectal toxicities associated with radiation treatment of prostate cancer, is a major …