Salt taste receptors and associated salty/salt taste-enhancing peptides: A comprehensive review of structure and function

B Le, B Yu, MS Amin, R Liu, N Zhang… - Trends in Food Science …, 2022 - Elsevier
Background Long-term high sodium diet consumption has been largely implicated in the
pathogenesis of several cardiovascular disease conditions. Non-sodium salts such as …

Physiology of the tongue with emphasis on taste transduction

ME Doyle, HU Premathilake, Q Yao… - Physiological …, 2023 - journals.physiology.org
The tongue is a complex multifunctional organ that interacts and senses both interoceptively
and exteroceptively. Although it is easily visible to almost all of us, it is relatively …

Maillard-reacted peptides from glucosamine-induced glycation exhibit a pronounced salt taste-enhancing effect

B Yu, W Wu, B Wang, N Zhang, KH Bak, OP Soladoye… - Food Chemistry, 2022 - Elsevier
Reducing salt intake, as one of the most cost-effective approaches, is congruent with
improved population health. Grass carp skin collagen was subjected to enzymatic hydrolysis …

Saltiness-enhancing peptides isolated from the Chinese commercial fermented soybean curds with potential applications in salt reduction

YP Chen, M Wang, I Blank, J Xu… - Journal of agricultural …, 2021 - ACS Publications
Salt is very important for human health and food seasoning. Recently, several peptides
isolated from natural food products have been reported exhibiting a salty taste or a saltiness …

Advances in flavor peptides with sodium-reducing ability: A review

T Gao, X Huang, X Chen, X Cai, J Huang… - Critical Reviews in …, 2023 - Taylor & Francis
Condiments (such as sodium chloride and glutamate sodium) cause consumers to ingest
too much sodium and may lead to a variety of diseases, thus decreasing their quality of life …

Prospects and challenges for the application of salty and saltiness-enhancing peptides in low-sodium meat products

R Chen, XC Liu, J Xiang, W Sun, I Tomasevic - Meat science, 2023 - Elsevier
A long-term high-sodium diet has been reported to increase the incidence of cardiovascular
diseases and other diseases, including osteoporosis, gastric cancer, stomach cancer, and …

[HTML][HTML] Kokumi taste active peptides modulate salt and umami taste

MR Rhyu, AY Song, EY Kim, HJ Son, Y Kim… - Nutrients, 2020 - mdpi.com
Kokumi taste substances exemplified by γ-glutamyl peptides and Maillard Peptides
modulate salt and umami tastes. However, the underlying mechanism for their action has not …

[HTML][HTML] Does ENaC work as sodium taste receptor in humans?

A Bigiani - Nutrients, 2020 - mdpi.com
Taste reception is fundamental for the proper selection of food and beverages. Among the
several chemicals recognized by the human taste system, sodium ions (Na+) are of …

Rare Variants in Genes Encoding Subunits of the Epithelial Na+ Channel Are Associated With Blood Pressure and Kidney Function

BM Blobner, A Kirabo, OB Kashlan, S Sheng… - …, 2022 - Am Heart Assoc
Background: The epithelial Na+ channel (ENaC) is intrinsically linked to fluid volume
homeostasis and blood pressure. Specific rare mutations in SCNN1A, SCNN1B, and …

Reaction Mixtures Rich in [γ-Glu](n≥1)-Arg Derived from Enzymatic Synthesis as Potential Salt and Umami Enhancers

J Wu, Y Sun, X Huan, C Cui - Journal of Agricultural and Food …, 2022 - ACS Publications
Some arginyl dipeptides and γ-glutamyl peptides have been identified as salt and umami
enhancers. These compounds provide an operable approach for reducing sodium uptake …