[HTML][HTML] Aptamers in diagnostics and treatment of viral infections
T Wandtke, J Woźniak, P Kopiński - Viruses, 2015 - mdpi.com
Aptamers are in vitro selected DNA or RNA molecules that are capable of binding a wide
range of nucleic and non-nucleic acid molecules with high affinity and specificity. They have …
range of nucleic and non-nucleic acid molecules with high affinity and specificity. They have …
Aptamers for viral detection and inhibition
Recent times have experienced more than ever the impact of viral infections in humans.
Viral infections are known to cause diseases not only in humans but also in plants and …
Viral infections are known to cause diseases not only in humans but also in plants and …
Selection of aptamers against live bacterial cells
Single-stranded DNA or RNA aptamer molecules have usually been selected against
purified target molecules. To eliminate the need of purifying target molecules on the cell …
purified target molecules. To eliminate the need of purifying target molecules on the cell …
Selection and analytical applications of aptamers binding microbial pathogens
DNA aptamers specifically recognizing microbial cells and viruses have a range of analytical
and therapeutic applications. This article describes recent advances in the development of …
and therapeutic applications. This article describes recent advances in the development of …
[HTML][HTML] Use of aptamers as diagnostics tools and antiviral agents for human viruses
VM González, ME Martín, G Fernández… - Pharmaceuticals, 2016 - mdpi.com
Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most
important factor in rapidly developing and epidemiologically dangerous diseases, such as …
important factor in rapidly developing and epidemiologically dangerous diseases, such as …
[HTML][HTML] Aptamers for anti-viral therapeutics and diagnostics
TH Kim, SW Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
Viral infections cause a host of fatal diseases and seriously affect every form of life from
bacteria to humans. Although most viral infections can receive appropriate treatment thereby …
bacteria to humans. Although most viral infections can receive appropriate treatment thereby …
The future of aptamers in medicine
M Khati - Journal of Clinical Pathology, 2010 - jcp.bmj.com
Aptamers, simply described as chemical antibodies, are synthetic oligonucleotide ligands or
peptides that can be isolated in vitro against diverse targets including toxins, bacterial and …
peptides that can be isolated in vitro against diverse targets including toxins, bacterial and …
[HTML][HTML] Aptamer-based therapeutics: new approaches to combat human viral diseases
Viruses replicate inside the cells of an organism and continuously evolve to contend with an
ever-changing environment. Many life-threatening diseases, such as AIDS, SARS, hepatitis …
ever-changing environment. Many life-threatening diseases, such as AIDS, SARS, hepatitis …
Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site: Miniperspective
SM Dibrov, J Parsons, M Carnevali… - Journal of medicinal …, 2014 - ACS Publications
The internal ribosome entry site (IRES) in the 5′ untranslated region (UTR) of the hepatitis
C virus (HCV) genome initiates translation of the viral polyprotein precursor. The unique …
C virus (HCV) genome initiates translation of the viral polyprotein precursor. The unique …