Glioblastoma (GBM) is the most lethal form of brain tumor, being characterized by the rapid
growth and invasion of the surrounding tissue. The current standard treatment for …

Focused ultrasound combined with microbubble-mediated intranasal delivery (FUSIN) is a
new brain drug delivery technique. FUSIN utilizes the nasal route for direct nose-to-brain …

Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumor with a short
survival rate. Extensive research is underway for the last two decades to find an effective …

In this study, a thermosensitive in situ gel nanoemulsion was formulated by a low energy
method for intranasal delivery of temozolomide to bypass the blood‐brain barrier and …

Targeting tumors has always been a herculean task. Moreover, the presence of blood brain
barrier (BBB) acts as a physical barrier and restricts the transportation of therapeutic …

Temozolomide presents significant anticancer activities in preclinical trials. However, its
clinical applications suffer from serious side effects owing to the high concentration in blood …

Some cancer cells elongate their telomeres through the ALT (alternative lengthening of
telomeres) pathway, which is based on homologous recombination for the addition of …

La régulation de la neurogenèse embryonnaire implique de nombreux facteurs intrinsèques
et extrinsèques délivrés avec une séquence temporelle stricte. Parmi ces facteurs, l'oxygène …