Oxidative stress in depression: the link with the stress response, neuroinflammation, serotonin, neurogenesis and synaptic plasticity

AS Correia, A Cardoso, N Vale - Antioxidants, 2023 - mdpi.com
Depression is a prevalent, complex, and highly debilitating disease. The full comprehension
of this disease is still a global challenge. Indeed, relapse, recurrency, and therapeutic …

The effects of microglia‐and astrocyte‐derived factors on neurogenesis in health and disease

T Araki, Y Ikegaya, R Koyama - European Journal of …, 2021 - Wiley Online Library
Hippocampal neurogenesis continues throughout life and has been suggested to play an
essential role in maintaining spatial cognitive function under physiological conditions. An …

Neuroinflammation and neurogenesis in Alzheimer's disease and potential therapeutic approaches

PS Sung, PY Lin, CH Liu, HC Su, KJ Tsai - International journal of …, 2020 - mdpi.com
In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …

Acute and long-term effects of adolescence stress exposure on rodent adult hippocampal neurogenesis, cognition, and behaviour

A Borsini, J Giacobbe, G Mandal, M Boldrini - Molecular Psychiatry, 2023 - nature.com
Adolescence represents a critical period for brain and behavioural health and characterised
by the onset of mood, psychotic and anxiety disorders. In rodents, neurogenesis is very …

Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review

B Zimmerman, B Rypma, G Gratton… - …, 2021 - Wiley Online Library
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

[HTML][HTML] Aging brain mechanics: Progress and promise of magnetic resonance elastography

LV Hiscox, H Schwarb, MDJ McGarry, CL Johnson - Neuroimage, 2021 - Elsevier
Novel neuroimaging techniques that can sensitivity characterize healthy brain aging and
detect subtle neuropathologies have enormous potential to assist in the early detection of …

Evidence for postnatal neurogenesis in the human amygdala

SS Roeder, P Burkardt, F Rost, J Rode… - Communications …, 2022 - nature.com
The human amygdala is involved in processing of memory, decision-making, and emotional
responses. Previous studies suggested that the amygdala may represent a neurogenic …

Three-dimensional cell cultures: the bridge between in vitro and in vivo models

O Urzì, R Gasparro, E Costanzo, A De Luca… - International Journal of …, 2023 - mdpi.com
Although historically, the traditional bidimensional in vitro cell system has been widely used
in research, providing much fundamental information regarding cellular functions and …

Psychedelics for acquired brain injury: a review of molecular mechanisms and therapeutic potential

J Allen, SS Dames, CJ Foldi, SR Shultz - Molecular Psychiatry, 2024 - nature.com
Acquired brain injury (ABI), such as traumatic brain injury and stroke, is a leading cause of
disability worldwide, resulting in debilitating acute and chronic symptoms, as well as an …

Stroke and neurogenesis: bridging clinical observations to new mechanistic insights from animal models

JP Passarelli, SM Nimjee, KL Townsend - Translational stroke research, 2024 - Springer
Stroke was the 2nd leading cause of death and a major cause of morbidity. Unfortunately,
there are limited means to promote neurological recovery post-stroke, but research has …