[HTML][HTML] Albendazole and mebendazole as anti-parasitic and anti-cancer agents: an update

JY Chai, BK Jung, SJ Hong - The Korean Journal of Parasitology, 2021 - ncbi.nlm.nih.gov
The use of albendazole and mebendazole, ie, benzimidazole broad-spectrum anthelmintics,
in treatment of parasitic infections, as well as cancers, is briefly reviewed. These drugs are …

Advances in vaccine development for human lymphatic filariasis

R Kalyanasundaram, V Khatri, N Chauhan - Trends in parasitology, 2020 - cell.com
According to the World Health Organization, over 880 million people are currently at risk of
acquiring lymphatic filariasis (LF) in over 52 countries worldwide. Current approaches to …

Safety and efficacy of mass drug administration with a single-dose triple-drug regimen of albendazole+ diethylcarbamazine+ ivermectin for lymphatic filariasis in …

L Tavul, M Laman, C Howard, B Kotty… - PLoS neglected …, 2022 - journals.plos.org
Background Papua New Guinea (PNG) has a high burden of lymphatic filariasis (LF) caused
by Wuchereria bancrofti, with an estimated 4.2 million people at risk of infection. A single co …

Efficacy and safety of a single dose of ivermectin, diethylcarbamazine, and albendazole for treatment of lymphatic filariasis in Cote d'Ivoire: an open-label randomized …

CM Bjerum, AF Ouattara, M Aboulaye… - Clinical Infectious …, 2020 - academic.oup.com
Background Improved drug regimens are needed to accelerate elimination of lymphatic
filariasis in Africa. This study determined whether a single co-administered dose of …

Factors associated with variation in single-dose albendazole pharmacokinetics: A systematic review and modelling analysis

C Whittaker, CB Chesnais, SDS Pion… - PLOS Neglected …, 2022 - journals.plos.org
Background Albendazole is an orally administered anti-parasitic medication with
widespread usage in a variety of both programmatic and clinical contexts. Previous work has …

Comparative safety surveillance of triple (IDA) versus dual therapy (DA) in mass drug administration for elimination of lymphatic filariasis in Kenya: A cohort event …

C Khaemba, A Barry, WP Omondi, E Kirui, M Oluka… - Drug Safety, 2023 - Springer
Introduction Dual diethylcarbamazine and albendazole (DA) therapy is the standard mass
drug administration (MDA) regimen for lymphatic filariasis in Kenya. Following the recent …

Delays in lymphatic filariasis elimination programmes due to COVID-19, and possible mitigation strategies

JM Prada, WA Stolk, EL Davis… - Transactions of the …, 2021 - academic.oup.com
Background In view of the current global coronavirus disease 2019 pandemic, mass drug
administration interventions for neglected tropical diseases, including lymphatic filariasis …

High-fat breakfast increases bioavailability of albendazole compared to low-fat breakfast: Single-dose study in healthy subjects

D Ochoa, M Saiz-Rodríguez… - Frontiers in …, 2021 - frontiersin.org
Purpose: Albendazole is a benzimidazole carbamate drug with anthelmintic and
antiprotozoal activity against intestinal and tissue parasites. It has been described that the …

Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections

A Schiefer, MP Hübner, A Krome… - PLoS neglected …, 2020 - journals.plos.org
Current efforts to eliminate the neglected tropical diseases onchocerciasis and lymphatic
filariasis, caused by the filarial nematodes Onchocerca volvulus and Wuchereria bancrofti or …

Safety and tolerability of ivermectin and albendazole mass drug administration in lymphatic filariasis endemic communities of Tanzania: a cohort event monitoring …

AM Fimbo, OM Minzi, BP Mmbando, P Gurumurthy… - Pharmaceuticals, 2022 - mdpi.com
Ivermectin and albendazole (IA) combination preventive chemotherapy to all at-risk
populations is deployed to eliminate lymphatic filariasis. Although safety monitoring is …