Nowadays in our developing and industrial world, humans' health or even their life is
threatened by exposure to poisons. In this situation, detecting a protective compound could …

The aim of this study was to investigate the therapeutic activity of isoquinoline alkaloid
berberine against cisplatin (CP)-induced nephrotoxicity in mice. Berberine was administered …

Highlights•Tadalafil mitigated cisplatin-induced testicular toxicity in male rats.•Tadalafil
antagonized cisplatin-induced oxidative stress and inflammatory markers.•Tadalafil acts by …

Cisplatin is widely used as one of the most effective anticancer agents in the treatment of
some neoplasms. Reproductive toxicity is the most common outcome associated with …

Background Cisplatin (CP) or cis-diammine dichloroplatinum (II) is a platinum based
standard antineoplastic drug which is used against variety of solid tumors and neoplasms …

The aim of this study was to investigate the renoprotective activity of chlorogenic acid (CA) in
a murine model of cisplatin (CP)-induced kidney injury. Male BALB/cN mice were gavaged …

This study investigated the probable protective effect of resveratrol against cisplatin-induced
testicular and epididymal toxicity in rats. Body weights of the animals showed no significant …

Background Cisplatin (CIS) is a chemotherapeutic agent widely used to cure several
cancers. It exerts detrimental cellular effects that restrain its clinical application as an …

Rosmarinic acid (RA) is a natural phenolic compound with a broad range of applications,
from food preservatives to cosmetics. Increasing amounts of evidence suggests its beneficial …

Background Cisplatin (CP), an effective anticancer agent, carries the risk of impairing
testicular function leading to infertility. The present study aimed at evaluating the protective …