Radioactive transition metals for imaging and therapy

E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Applications of radiocomplexes with thiosemicarbazones and bis (thiosemicarbazones) in diagnostic and therapeutic nuclear medicine

GL Parrilha, RG dos Santos, H Beraldo - Coordination Chemistry Reviews, 2022 - Elsevier
Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

Copper complexes of bis (thiosemicarbazones): from chemotherapeutics to diagnostic and therapeutic radiopharmaceuticals

BM Paterson, PS Donnelly - Chemical Society Reviews, 2011 - pubs.rsc.org
The molecules known as bis (thiosemicarbazones) derived from 1, 2-diones can act as
tetradentate ligands for Cu (II), forming stable, neutral complexes. As a family, these …

[HTML][HTML] Development of copper based drugs, radiopharmaceuticals and medical materials

P Szymański, T Frączek, M Markowicz… - Biometals, 2012 - Springer
Copper is one of the most interesting elements for various biomedical applications. Copper
compounds show vast array of biological actions, including anti-inflammatory, anti …

Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals

S Bhattacharyya, M Dixit - Dalton transactions, 2011 - pubs.rsc.org
Metallic radionuclides are the mainstay of both diagnostic and therapeutic
radiopharmaceuticals. Therapeutic nuclear medicine is less advanced but has tremendous …

[HTML][HTML] Assessment of tissue perfusion by contrast-enhanced ultrasound

E Quaia - European radiology, 2011 - Springer
Contrast-enhanced ultrasound (CEUS) with microbubble contrast agents is a new imaging
technique for quantifying tissue perfusion. CEUS presents several advantages over other …

The role of coordination chemistry in the development of copper and rhenium radiopharmaceuticals

PS Donnelly - Dalton Transactions, 2011 - pubs.rsc.org
There are several isotopes of copper and rhenium that are of interest in the development of
new molecular imaging or radiotherapeutic agents. This perspective article highlights the …

[HTML][HTML] Radionuclide generators: the prospect of availing PET radiotracers to meet current clinical needs and future research demands

A Dash, R Chakravarty - American journal of nuclear medicine and …, 2019 - ncbi.nlm.nih.gov
Targeted molecular imaging with positron emission tomography (PET) constitutes a
successful technique for detecting and diagnosing disease conditions promptly and …

Versatile New Bis(thiosemicarbazone) Bifunctional Chelators: Synthesis, Conjugation to Bombesin(7−14)-NH2, and Copper-64 Radiolabeling

BM Paterson, JA Karas, DB Scanlon, JM White… - Inorganic …, 2010 - ACS Publications
New bifunctional derivatives of diacetyl-bis (4-methylthiosemicarbazone)(H2atsm) have
been prepared by a selective transamination reaction of a new dissymmetric bis …