Roles of Krüppel‐like factor 4 in normal homeostasis, cancer and stem cells

PM Evans, C Liu - Acta biochimica et biophysica Sinica, 2008 - Wiley Online Library
Krüppel‐like factor 4 (KLF4) is a zinc finger‐type transcription factor expressed in a variety of
tissues, including the epithelium of the intestine and the skin, and it plays an important role …

Biology of Krüppel‐like factor 6 transcriptional regulator in cell life and death

V Andreoli, RC Gehrau, JL Bocco - IUBMB life, 2010 - Wiley Online Library
An essential role for the Krüppel-like transcription factor family has been determined in the
regulation of remarkable processes including cell proliferation, differentiation, signal …

Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1

D Li, S Yea, S Li, Z Chen, G Narla, M Banck… - Journal of Biological …, 2005 - ASBMB
Preadipocyte differentiation occurs during distinct periods of human development and is a
key determinant of body mass. Transcriptional events underlying adipogenesis continue to …

Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer

HL Reeves, G Narla, O Ogunbiyi, AI Haq, A Katz… - Gastroenterology, 2004 - Elsevier
Background & Aims: Kruppel-like factor 6 (KLF6) is a ubiquitous zinc finger tumor
suppressor that is often mutated in prostate cancer. Our aims were to establish the frequency …

Kruppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells

G Ito, M Uchiyama, M Kondo, S Mori, N Usami… - Cancer research, 2004 - AACR
Krüppel-like factor 6 (KLF6) is a ubiquitously expressed zinc finger transcriptional factor,
which has been suggested to be a candidate tumor suppressor gene in prostate cancer and …

Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6

N Matsumoto, A Kubo, H Liu, K Akita, F Laub… - Blood, 2006 - ashpublications.org
Krüppel-like factor 6 (KLF6) is a member of a growing family of transcription factors that
share a common 3 C2H2 zinc finger DNA binding domain and have broad activity in …

Transcription factors that regulate trophoblast development and function

KJ Baines, SJ Renaud - Progress in molecular biology and translational …, 2017 - Elsevier
The placenta is a transient organ that plays a critical role in sustaining pregnancy and
supporting fetal growth and nutrition. The placental epithelium is comprised of trophoblast …

A new role for the Krüppel-like transcription factor KLF6 as an inhibitor of c-Jun proto-oncoprotein function

DA Slavin, NP Koritschoner, CC Prieto, FJ López-Díaz… - Oncogene, 2004 - nature.com
Krüppel-like transcription factors (KLFs) represent one of the most diverse set of regulators
in vertebrate organisms. KLF family members are involved in cell proliferation and …

[HTML][HTML] Tough beginnings: alterations in the transcriptome of cloned embryos during the first two cell cycles

R Vassena, Z Han, S Gao, DA Baldwin, RM Schultz… - Developmental …, 2007 - Elsevier
Cloned embryos produced by somatic cell nuclear transfer (SCNT) display a plethora of
phenotypic characteristics that make them different from fertilized embryos, indicating …

Transcriptional activation of the human inducible nitric-oxide synthase promoter by Krüppel-like factor 6

VG Warke, MP Nambiar, S Krishnan, K Tenbrock… - Journal of Biological …, 2003 - ASBMB
Nitric oxide is a ubiquitous free radical that plays a key role in a broad spectrum of signaling
pathways in physiological and pathophysiological processes. We have explored the …