Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond
Platelets are small anucleate blood cells generated from megakaryocytes in the bone
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …
[HTML][HTML] Platelets in hemostasis and thrombosis: Novel mechanisms of fibrinogen-independent platelet aggregation and fibronectin-mediated protein wave of …
Platelets are small anucleate cells generated from megakaryocytes in the bone marrow.
Although platelet generation, maturation, and clearance are still not fully understood …
Although platelet generation, maturation, and clearance are still not fully understood …
Regulation of platelet function and thrombosis by omega-3 and omega-6 polyunsaturated fatty acids
R Adili, M Hawley, M Holinstat - Prostaglandins & other lipid mediators, 2018 - Elsevier
Thrombosis is the most common underlying pathology responsible for morbidity and
mortality in cardiovascular disease (CVD). Platelet adhesion, activation, and aggregation …
mortality in cardiovascular disease (CVD). Platelet adhesion, activation, and aggregation …
Oligomeric cocoa procyanidins possess enhanced bioactivity compared to monomeric and polymeric cocoa procyanidins for preventing the development of obesity …
MR Dorenkott, LE Griffin, KM Goodrich… - Journal of agricultural …, 2014 - ACS Publications
There is interest in the potential of cocoa flavanols, including monomers and procyanidins,
to prevent obesity and type-2 diabetes. Fermentation and processing of cocoa beans …
to prevent obesity and type-2 diabetes. Fermentation and processing of cocoa beans …
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis
Platelet adhesion and aggregation at the sites of vascular injury are key events for
thrombosis and haemostasis. It has been well demonstrated that interaction between …
thrombosis and haemostasis. It has been well demonstrated that interaction between …
Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation
AL Banka, MV Guevara, ER Brannon… - Nature …, 2023 - nature.com
The combination of inflammation and thrombosis is a hallmark of many cardiovascular
diseases. Under such conditions, platelets are recruited to an area of inflammation by …
diseases. Under such conditions, platelets are recruited to an area of inflammation by …
Plant food delphinidin-3-glucoside significantly inhibits platelet activation and thrombosis: novel protective roles against cardiovascular diseases
Delphinidin-3-glucoside (Dp-3-g) is one of the predominant bioactive compounds of
anthocyanins in many plant foods. Although several anthocyanin compounds have been …
anthocyanins in many plant foods. Although several anthocyanin compounds have been …
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIbα
The interaction of platelet GPIbα with von Willebrand factor (VWF) is essential to initiate
platelet adhesion and thrombosis, particularly under high shear stress conditions. However …
platelet adhesion and thrombosis, particularly under high shear stress conditions. However …
Extracellular matrix proteins in the regulation of thrombus formation
Extracellular matrix proteins in the regulation of thrombus... : Current Opinion in Hematology
Extracellular matrix proteins in the regulation of thrombus formation : Current Opinion in …
Extracellular matrix proteins in the regulation of thrombus formation : Current Opinion in …
Striking immune phenotypes in gene-targeted mice are driven by a copy-number variant originating from a commercially available C57BL/6 strain
We describe a homozygous copy-number variant that disrupts the function of Dock2 in a
commercially available C57BL/6 mouse strain that is widely used for backcrossing. This …
commercially available C57BL/6 mouse strain that is widely used for backcrossing. This …