Could lower testosterone in older men explain higher COVID-19 morbidity and mortalities?

LM Montano, B Sommer, H Solis-Chagoyan… - International Journal of …, 2022 - mdpi.com
The health scourge imposed on humanity by the COVID-19 pandemic seems not to recede.
This fact warrants refined and novel ideas analyzing different aspects of the illness. One …

Transient receptor potential cation channel subfamily V (TRPV) and its importance in asthma.

J Reyes-García, A Carbajal-Garcia… - European journal of …, 2022 - Elsevier
Transient receptor potential (TRP) ion channels play critical roles in physiological and
pathological conditions. Increasing evidence has unveiled the contribution of TRP vanilloid …

Sex hormones and lung inflammation

J Reyes-Garcia, LM Montano… - Lung Inflammation in …, 2021 - Springer
Inflammation is a characteristic marker in numerous lung disorders. Several immune cells,
such as macrophages, dendritic cells, eosinophils, as well as T and B lymphocytes …

Detecting the multiomics signatures of factor-specific inflammatory effects on airway smooth muscles

YH Zhang, Z Li, T Zeng, L Chen, H Li, T Huang… - Frontiers in …, 2021 - frontiersin.org
Smooth muscles are a specific muscle subtype that is widely identified in the tissues of
internal passageways. This muscle subtype has the capacity for controlled or regulated …

Estrogen receptors differentially regulate intracellular calcium handling in human nonasthmatic and asthmatic airway smooth muscle cells

S Bhallamudi, J Connell, CM Pabelick… - … of Physiology-Lung …, 2020 - journals.physiology.org
Asthma is defined as chronic inflammation of the airways and is characterized by airway
remodeling, hyperresponsiveness, and acute bronchoconstriction of airway smooth muscle …

Androgen effects on the adrenergic system of the vascular, airway, and cardiac myocytes and their relevance in pathological processes

A Carbajal-García, J Reyes-García… - International Journal of …, 2020 - Wiley Online Library
Introduction. Androgen signaling comprises nongenomic and genomic pathways.
Nongenomic actions are not related to the binding of the androgen receptor (AR) and occur …

Interactions between calcium regulatory pathways and mechanosensitive channels in airways

Y Yao, NA Borkar, M Zheng, S Wang… - Expert Review of …, 2023 - Taylor & Francis
Introduction Asthma is a chronic lung disease influenced by environmental and inflammatory
triggers and involving complex signaling pathways across resident airway cells such as …

Estrogenic modulation of ionic channels, pumps and exchangers in Airway smooth muscle

BS Romero-Martínez, B Sommer… - International Journal of …, 2023 - mdpi.com
To preserve ionic homeostasis (primarily Ca2+, K+, Na+, and Cl−), in the airway smooth
muscle (ASM) numerous transporters (channels, exchangers, and pumps) regulate the influx …

The modulation by anesthetics and analgesics of respiratory rhythm in the nervous system

X Hao, Y Yang, J Liu, D Zhang, M Ou… - Current …, 2024 - benthamdirect.com
Rhythmic eupneic breathing in mammals depends on the coordinated activities of the neural
system that sends cranial and spinal motor outputs to respiratory muscles. These outputs …

Reactive oxygen species, mitochondrial membrane potential, and cellular membrane potential are predictors of e-liquid induced cellular toxicity

E Correia-Álvarez, JE Keating, G Glish… - Nicotine and …, 2020 - academic.oup.com
Introduction The use of flavors in electronic cigarettes appeals to adults and never-smoking
youth. Consumption has rapidly increased over the last decade, and in the US market alone …