Spectroscopic insights with molecular docking and molecular dynamic simulation studies of anticancer drug 5-Fluorouracil targeting human pyruvate kinase m2

M Priyadarshinee, B Dehury, S Mishra… - Journal of …, 2024 - Taylor & Francis
This study was conducted to test the efficacy of 5-fluorouracil (5-FU) as an anticancer drug
against the human pyruvate kinase isozyme M2 (PKM2) using spectroscopic, molecular …

Exploring imidazo[4,5-g]quinoline-4,9-dione derivatives as Acinetobacter baumannii efflux pump inhibitor: an in silico approach

P Brindangnanam, K Ashokkumar… - Journal of …, 2023 - Taylor & Francis
Antimicrobial resistance (AMR) is fast becoming a medical crisis affecting the entire global
population. World Health Organization (WHO) statistics show that globally 0.7 million people …

[PDF][PDF] Multidrug Efflux Protein Families in Bacteria: ABC, RND, MFS, SMR, MATE, PACE, AbgT (An Update)

I Ahmad, M Ali, R Ali, N Nawaz, SG Patching - researchgate.net
Multidrug efflux proteins, also known as efflux pumps, are one of the major mechanisms that
bacteria have evolved for their resistance against antimicrobial agents. Gram-negative …