The entropy-controlled strategy in self-assembling systems
X Zhang, X Dai, L Gao, D Xu, H Wan, Y Wang… - Chemical Society …, 2023 - pubs.rsc.org
Self-assembly of various building blocks has been considered as a powerful approach to
generate novel materials with tailorable structures and optimal properties. Understanding …
generate novel materials with tailorable structures and optimal properties. Understanding …
Enzyme fusions in biocatalysis: coupling reactions by pairing enzymes
FS Aalbers, MW Fraaije - ChemBioChem, 2019 - Wiley Online Library
One approach to bringing enzymes together for multienzyme biocatalysis is genetic fusion.
This enables the production of multifunctional enzymes that can be used for whole‐cell …
This enables the production of multifunctional enzymes that can be used for whole‐cell …
[HTML][HTML] Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia
Chimeric antigen receptor (CAR) T cell therapy is effective in lymphoid malignancies, but
there has been limited data in myeloid cancers. Here, we start with a CD27-based CAR to …
there has been limited data in myeloid cancers. Here, we start with a CD27-based CAR to …
A magnetic protein biocompass
The notion that animals can detect the Earth's magnetic field was once ridiculed, but is now
well established. Yet the biological nature of such magnetosensing phenomenon remains …
well established. Yet the biological nature of such magnetosensing phenomenon remains …
Tuning the flexibility of glycine-serine linkers to allow rational design of multidomain proteins
M Van Rosmalen, M Krom, M Merkx - Biochemistry, 2017 - ACS Publications
Flexible polypeptide linkers composed of glycine and serine are important components of
engineered multidomain proteins. We have previously shown that the conformational …
engineered multidomain proteins. We have previously shown that the conformational …
Improving the reproducibility, accuracy, and stability of an electrochemical biosensor platform for point-of-care use
LC Chen, E Wang, CS Tai, YC Chiu, CW Li… - Biosensors and …, 2020 - Elsevier
Electrochemical biosensors possess numerous desirable qualities for target detection, such
as portability and ease of use, and are often considered for point-of-care (POC) …
as portability and ease of use, and are often considered for point-of-care (POC) …
[HTML][HTML] Design and biocatalytic applications of genetically fused multifunctional enzymes
Fusion proteins, understood as those created by joining two or more genes that originally
encoded independent proteins, have numerous applications in biotechnology, from …
encoded independent proteins, have numerous applications in biotechnology, from …
Protein mediated enzyme immobilization
AA Caparco, DR Dautel, JA Champion - Small, 2022 - Wiley Online Library
Enzyme immobilization is an essential technology for commercializing biocatalysis. It
imparts stability, recoverability, and other valuable features that improve the effectiveness of …
imparts stability, recoverability, and other valuable features that improve the effectiveness of …
Spatial organization of multi-enzyme biocatalytic cascades
MB Quin, KK Wallin, G Zhang… - Organic & biomolecular …, 2017 - pubs.rsc.org
Industrial biocatalysis is an economically attractive option for the production of valuable
chemicals. Our repertoire of cheap building blocks and commodity target molecules is vastly …
chemicals. Our repertoire of cheap building blocks and commodity target molecules is vastly …
Combinatorial metabolic pathway assembly approaches and toolkits for modular assembly
R Young, M Haines, M Storch, PS Freemont - Metabolic Engineering, 2021 - Elsevier
Synthetic Biology is a rapidly growing interdisciplinary field that is primarily built upon
foundational advances in molecular biology combined with engineering design principles …
foundational advances in molecular biology combined with engineering design principles …