Protein kinase CK2 ('casein kinase II') has traditionally been classified as a messenger-
independent protein serine/threonine kinase that is typically found in tetrameric complexes …

CK2 is a highly conserved protein serine/threonine kinase that is ubiquitously distributed in
eukaryotes, constitutively active and has been implicated in multiple cellular functions, as …

Malignant transformation and maintenance of the malignant phenotype depends on
oncogenic and non-oncogenic proteins that are essential to mediate oncogene signaling …

Accumulating evidence indicates that interactions between the epidermal growth factor
receptor (EGFR) and the nonreceptor tyrosine kinase c-Src may contribute to an aggressive …

Phorbol esters (eg, TPA) activate protein kinase C (PKC), increase connexin43 (Cx43)
phosphorylation, and decrease cell–cell communication via gap junctions in many cell …

Glycogen synthase kinase-3 (GSK-3) is a critical, negative regulator of diverse signaling
pathways. Lithium is a direct inhibitor of GSK-3 and has been widely used to test the putative …

Our ability to model the dynamics of signal transduction networks will depend on accurate
methods to quantify levels of protein phosphorylation on a global scale. Here we describe a …

13 S condensin is a multisubunit protein complex essential for mitotic chromosome
condensation in Xenopus egg extracts. Purified 13 S condensin introduces positive …

Protein kinase CK2 (also termed casein kinase-2 or-II) is a ubiquitous Ser/Thr-specific
protein kinase required for viability and for cell cycle progression. CK2 is especially elevated …

Summary N 6-Methyladenosine (m 6 A) modification is the major chemical modification in
mRNA that controls fundamental biological processes, including cell proliferation. Herein …