Co-crystallization of drugs with benign co-formers is promising for enhancing dissolution
rate of poorly soluble drugs. The selection of safe and pharmacologically inert co-formers is …

Background: Pharmaceutical cocrystal is an emerging approach to tailor physicochemical
and mechanical properties of drug substances. Cocrystals are composed of API and …

Solid solubility is a significant physical property for a drug development and design. In the
present work, the domperidone solubility, which has less study in the near-term, was …

Materials and Methods: Binary and ternary solid dispersions were prepared by fusion
method. They were characterized by solubility study, in vitro dissolution, dissolution …

Spray-dried aqueous extract from citrus by-product (“pastazzo”, ExO) was studied to
evaluate the polyphenols content, the antioxidant properties and the inhibition of …

Erectile dysfunction (ED) is the most important disorder after premature ejaculation for
sexual activity in men. Vardenafil hydrochloride (VH) is an oral therapy for the treatment of …

Sulpiride (SUL) is a dopamine D2-receptor antagonist used for management of GIT
disturbance and it has anti-psychotic activities based on the administered dose. SUL …

Purpose: The current work aimed to develop promising Fexofenadine hydrochloride (FXD)
liquisolid tablets able to increase its oral bioavailability and shorten time to reach maximum …

In the present research work, an attempt was made to improve the solubility and dissolution
rate of a poorly soluble drug, Gliclazide by solid dispersion method using soluplus and …

Rofecoxib (ROF), a potent selective COX-II inhibitor NSAID, has been withdrawn from the
market due to its high risk on patients with cardiovascular disorders (CVD). In the current …