Aquaporin-4 functionality and virchow-robin space water dynamics: physiological model for neurovascular coupling and glymphatic flow

T Nakada, IL Kwee, H Igarashi, Y Suzuki - International Journal of …, 2017 - mdpi.com
The unique properties of brain capillary endothelium, critical in maintaining the blood-brain
barrier (BBB) and restricting water permeability across the BBB, have important …

Understanding Functional Neurological Disorder: Recent Insights and Diagnostic Challenges

I Mavroudis, D Kazis, FZ Kamal, IL Gurzu… - International Journal of …, 2024 - mdpi.com
Functional neurological disorder (FND), formerly called conversion disorder, is a condition
characterized by neurological symptoms that lack an identifiable organic purpose. These …

Relationships linking emotional, motor, cognitive and GABAergic dysfunctions in dystrophin-deficient mdx mice

C Vaillend, R Chaussenot - Human molecular genetics, 2017 - academic.oup.com
Alterations in the Duchenne muscular dystrophy (DMD) gene have been associated with
enhanced stress reactivity in vertebrate species, suggesting a role for brain dystrophin in …

Social stress is lethal in the mdx model of Duchenne muscular dystrophy

M Razzoli, A Lindsay, ML Law, CM Chamberlain… - …, 2020 - thelancet.com
Background Duchenne muscular dystrophy (DMD) is caused by the loss of dystrophin.
Severe and ultimately lethal, DMD progresses relatively slowly in that patients become …

Startle responses in Duchenne muscular dystrophy: a novel biomarker of brain dystrophin deficiency

K Maresh, A Papageorgiou, D Ridout, NA Harrison… - Brain, 2023 - academic.oup.com
Duchenne muscular dystrophy (DMD) is characterized by loss of dystrophin in muscle,
however patients also have variable degree of intellectual disability and neurobehavioural …

[HTML][HTML] Cognitive impairment appears progressive in the mdx mouse

E Bagdatlioglu, P Porcari, E Greally, AM Blamire… - Neuromuscular …, 2020 - Elsevier
Duchenne muscular dystrophy (DMD) is an X-linked recessive muscle wasting disease
caused by mutations in the DMD gene, which encodes the large cytoskeletal protein …

[HTML][HTML] The unconditioned fear response in vertebrates deficient in dystrophin

S Gharibi, C Vaillend, A Lindsay - Progress in Neurobiology, 2024 - Elsevier
Dystrophin loss due to mutations in the Duchenne muscular dystrophy (DMD) gene is
associated with a wide spectrum of neurocognitive comorbidities, including an aberrant …

Laminin α2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development

M Ahmed, LN Marziali, E Arenas, ML Feltri… - …, 2019 - journals.biologists.com
Development of the central nervous system requires coordination of the proliferation and
differentiation of neural stem cells. Here, we show that laminin alpha 2 (lm-α2) is a …

Abnormal Expression of Synaptic and Extrasynaptic GABAA Receptor Subunits in the Dystrophin-Deficient mdx Mouse

F Zarrouki, S Goutal, O Vacca, L Garcia… - International Journal of …, 2022 - mdpi.com
Duchenne muscular dystrophy (DMD) is a neurodevelopmental disorder primarily caused by
the loss of the full-length Dp427 dystrophin in both muscle and brain. The basis of the …

In vivo cerebellar circuit function is disrupted in an mdx mouse model of Duchenne muscular dystrophy

TL Stay, LN Miterko, M Arancillo… - Disease Models & …, 2020 - journals.biologists.com
Duchenne muscular dystrophy (DMD) is a debilitating and ultimately lethal disease involving
progressive muscle degeneration and neurological dysfunction. DMD is caused by …