Macrophage phenotypes and functions: resolving inflammation and restoring homeostasis
P Rodríguez-Morales, RA Franklin - Trends in Immunology, 2023 - cell.com
Inflammation must be tightly regulated to both defend against pathogens and restore tissue
homeostasis. The resolution of inflammatory responses is a dynamic process orchestrated …
homeostasis. The resolution of inflammatory responses is a dynamic process orchestrated …
Innate immunity and interferon in SARS-CoV-2 infection outcome
Innate immunity and the actions of type I and III interferons (IFNs) are essential for protection
from SARS-CoV-2 and COVID-19. Each is induced in response to infection and serves to …
from SARS-CoV-2 and COVID-19. Each is induced in response to infection and serves to …
Recruited atypical Ly6G+ macrophages license alveolar regeneration after lung injury
C Ruscitti, J Abinet, P Maréchal, M Meunier… - Science …, 2024 - science.org
The lung is constantly exposed to airborne pathogens and particles that can cause alveolar
damage. Hence, appropriate repair responses are essential for gas exchange and life. Here …
damage. Hence, appropriate repair responses are essential for gas exchange and life. Here …
Bacteriophage T4 as a Protein-Based, Adjuvant-and Needle-Free, Mucosal Pandemic Vaccine Design Platform
The COVID-19 pandemic has transformed vaccinology. Rapid deployment of mRNA
vaccines has saved countless lives. However, these platforms have inherent limitations …
vaccines has saved countless lives. However, these platforms have inherent limitations …
Comparative single-cell analysis reveals IFN-γ as a driver of respiratory sequelae after acute COVID-19
Postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection (PASC) represent an urgent public health challenge and are estimated to affect …
infection (PASC) represent an urgent public health challenge and are estimated to affect …
Inhalation drug delivery in combating pulmonary infections: Advances and challenges
Pulmonary infections (PIs) are contributing as a significant cause of mortality across the
world. The clinical applications of a variety of therapeutics approved for PIs have been …
world. The clinical applications of a variety of therapeutics approved for PIs have been …
[HTML][HTML] Pulmonary delivery of silver nanoparticles prevents influenza infection by recruiting and activating lymphoid cells
L Martín-Faivre, L Prince, C Cornu, B Villeret… - Biomaterials, 2025 - Elsevier
Silver nanoparticles (AgNPs) are a potential antiviral agent due to their ability to disrupt the
viral particle or alter the virus metabolism inside the host cell. In vitro, AgNPs exhibit antiviral …
viral particle or alter the virus metabolism inside the host cell. In vitro, AgNPs exhibit antiviral …
An aberrant immune–epithelial progenitor niche drives viral lung sequelae
The long-term physiological consequences of respiratory viral infections, particularly in the
aftermath of the COVID-19 pandemic—termed post-acute sequelae of SARS-CoV-2 (PASC) …
aftermath of the COVID-19 pandemic—termed post-acute sequelae of SARS-CoV-2 (PASC) …
Postinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report
Continued improvements in the treatment of pulmonary infections have paradoxically
resulted in a growing challenge of individuals with postinfectious pulmonary complications …
resulted in a growing challenge of individuals with postinfectious pulmonary complications …
Regional specialization within the mammalian respiratory immune system
DPH van Konijnenburg, PA Nigrovic, I Zanoni - Trends in Immunology, 2024 - cell.com
The respiratory tract is exposed to infection from inhaled pathogens, including viruses,
bacteria, and fungi. So far, a comprehensive assessment that integrates common and …
bacteria, and fungi. So far, a comprehensive assessment that integrates common and …