On time: developmental timing within and across species

J Garcia-Ojalvo, A Bulut-Karslioglu - Development, 2023 - journals.biologists.com
Organisms across species differ in the relative size and complexity of their tissues to serve
the specific purposes of the host. Correct timing is a crucial ingredient in the development of …

[HTML][HTML] The stem cell zoo for comparative studies of developmental tempo

J Lázaro, J Sochacki, M Ebisuya - Current Opinion in Genetics & …, 2024 - Elsevier
Highlights•Pluripotent stem cells can be used to model cell-intrinsic developmental
tempo.•The stem cell zoo allows developmental studies of unconventional …

Combinatorial microRNA activity is essential for the transition of pluripotent cells from proliferation into dormancy

DP Iyer, L Moyon, L Wittler, CY Cheng… - Genome …, 2024 - genome.cshlp.org
Dormancy is a key feature of stem cell function in adult tissues as well as in embryonic cells
in the context of diapause. The establishment of dormancy is an active process that involves …

TET activity safeguards pluripotency throughout embryonic dormancy

M Stötzel, CY Cheng, IA IIik, AS Kumar… - Nature Structural & …, 2024 - nature.com
Dormancy is an essential biological process for the propagation of many life forms through
generations and stressful conditions. Early embryos of many mammals are preservable for …

Unraveling the impact of ZZZ3 on the mTOR/ribosome pathway in human embryonic stem cells homeostasis

ML Conte, V Lucchino, S Scalise, C Zannino… - Stem Cell Reports, 2024 - cell.com
Embryonic stem cells (ESCs) are defined as stem cells with self-renewing and differentiation
capabilities. These unique properties are tightly regulated and controlled by complex …

Transitions in development–an interview with

A Bulut-Karslioglu - 2023 - journals.biologists.com
Aydan Bulut-Karslioglu is a Group Leader at the Max Planck Institute for Molecular Genetics,
Germany, where her research focuses on the epigenetic and metabolic mechanisms …

[PDF][PDF] Giada Rossignoli, 6 Maria Stella Murfuni, Chiara Cicconetti, 3, 4 Luana Scaramuzzino, Danilo Swann Matassa, 5 Anna Procopio, Graziano Martello, 6 Giovanni …

ML Conte, V Lucchino, S Scalise, C Zannino, D Valente - researchgate.net
Embryonic stem cells (ESCs) are defined as stem cells with self-renewing and differentiation
capabilities. These unique properties are tightly regulated and controlled by complex …

Embryos burn fat in standby

VA van der Weijden, A Bulut-Karslioğlu, D Jiang… - Trends in Cell …, 2024 - cell.com
Embryonic and adult stem cells enable development and regeneration. Embryonic cells, like
adult stem cells, can enter dormancy as part of their lifecycle. Recent evidence suggests that …