Zebrafish: a model system for the study of human disease
K Dooley, LI Zon - Current opinion in genetics & development, 2000 - Elsevier
The zebrafish (Danio rerio) is a powerful model organism for the study of vertebrate biology,
being well suited to both developmental and genetic analysis. Large-scale genetic screens …
being well suited to both developmental and genetic analysis. Large-scale genetic screens …
[HTML][HTML] The zebrafish eye—a paradigm for investigating human ocular genetics
R Richardson, D Tracey-White, A Webster, M Moosajee - Eye, 2017 - nature.com
Although human epidemiological and genetic studies are essential to elucidate the
aetiology of normal and aberrant ocular development, animal models have provided us with …
aetiology of normal and aberrant ocular development, animal models have provided us with …
A genetic screen for mutations affecting embryogenesis in zebrafish
Systematic genome-wide mutagenesis screens for embryonic phenotypes have been
instrumental in the understanding of invertebrate and plant development. Here, we report …
instrumental in the understanding of invertebrate and plant development. Here, we report …
nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate
JA Lister, CP Robertson, T Lepage… - …, 1999 - journals.biologists.com
We report the isolation and identification of a new mutation affecting pigment cell fate in the
zebrafish neural crest. Homozygous nacre (nac w2) mutants lack melanophores throughout …
zebrafish neural crest. Homozygous nacre (nac w2) mutants lack melanophores throughout …
Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo
DYR Stainier, B Fouquet, JN Chen, KS Warren… - …, 1996 - journals.biologists.com
As part of a large-scale mutagenesis screen of the zebrafish genome, we have identified 58
mutations that affect the formation and function of the cardiovascular system. The …
mutations that affect the formation and function of the cardiovascular system. The …
Zebrafish—As an integrative model for twenty‐first century toxicity testing
NS Sipes, S Padilla, TB Knudsen - Birth Defects Research Part …, 2011 - Wiley Online Library
The zebrafish embryo is a useful small model for investigating vertebrate development
because of its transparency, low cost, transgenic and morpholino capabilities, conservation …
because of its transparency, low cost, transgenic and morpholino capabilities, conservation …
Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function
IA Drummond, A Majumdar, H Hentschel… - …, 1998 - journals.biologists.com
The zebrafish pronephric kidney provides a simplified model of nephron development and
epithelial cell differentiation which is amenable to genetic analysis. The pronephros consists …
epithelial cell differentiation which is amenable to genetic analysis. The pronephros consists …
Early retinal development in the zebrafish, Danio rerio: Light and electron microscopic analyses
EA Schmitt, JE Dowling - Journal of Comparative Neurology, 1999 - Wiley Online Library
The morphological differentiation of the zebrafish retina was analyzed by using light (LM)
and transmission electron (TEM) microscopy between the time of initial ganglion cell …
and transmission electron (TEM) microscopy between the time of initial ganglion cell …
Linking genes to brain, behavior and neurological diseases: what can we learn from zebrafish?
S Guo - Genes, Brain and Behavior, 2004 - Wiley Online Library
How our brain is wired and subsequently generates functional output, ranging from sensing
and locomotion to emotion, decision‐making and learning and memory, remains poorly …
and locomotion to emotion, decision‐making and learning and memory, remains poorly …