Contemporary management of cardiogenic shock: a scientific statement from the American Heart Association

S Van Diepen, JN Katz, NM Albert, TD Henry… - Circulation, 2017 - Am Heart Assoc
Cardiogenic shock is a high-acuity, potentially complex, and hemodynamically diverse state
of end-organ hypoperfusion that is frequently associated with multisystem organ failure …

[HTML][HTML] Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

H Bugger, K Pfeil - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
Despite major progress in interventional and medical treatments, myocardial infarction (MI)
and subsequent development of heart failure (HF) are still associated with high mortality …

The biological basis for cardiac repair after myocardial infarction: from inflammation to fibrosis

SD Prabhu, NG Frangogiannis - Circulation research, 2016 - Am Heart Assoc
In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …

A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair

K Sun, Y Li, J Jin - Signal transduction and targeted therapy, 2021 - nature.com
The response of immune cells in cardiac injury is divided into three continuous phases:
inflammation, proliferation and maturation. The kinetics of the inflammatory and proliferation …

A review of the molecular mechanisms underlying the development and progression of cardiac remodeling

L Schirone, M Forte, S Palmerio, D Yee… - Oxidative medicine …, 2017 - Wiley Online Library
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter
the existing structure of the heart, leading to cardiac dysfunction. Among the complex …

IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation

M Jung, Y Ma, RP Iyer, KY DeLeon-Pennell… - Basic research in …, 2017 - Springer
Inflammation resolution is important for scar formation following myocardial infarction (MI)
and requires the coordinated actions of macrophages and fibroblasts. In this study, we …

Luteolin protects against diabetic cardiomyopathy by inhibiting NF-κB-mediated inflammation and activating the Nrf2-mediated antioxidant responses

L Li, W Luo, Y Qian, W Zhu, J Qian, J Li, Y Jin, X Xu… - Phytomedicine, 2019 - Elsevier
Background Diabetes mellitus is a well-known risk factor for the development of heart failure.
Inflammation and oxidative stress play a key role in the development of diabetic …

YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction

MM Mia, DM Cibi, SAB Abdul Ghani, W Song… - PLoS …, 2020 - journals.plos.org
Adverse cardiac remodeling after myocardial infarction (MI) causes structural and functional
changes in the heart leading to heart failure. The initial post-MI pro-inflammatory response …

[HTML][HTML] MOF-derived bimetallic nanozyme to catalyze ROS scavenging for protection of myocardial injury

K Xiang, H Wu, Y Liu, S Wang, X Li, B Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Rationale: Myocardial injury triggers intense oxidative stress, inflammatory response, and
cytokine release, which are essential for myocardial repair and remodeling. Excess reactive …

Strategies for the chemical and biological functionalization of scaffolds for cardiac tissue engineering: a review

M Tallawi, E Rosellini, N Barbani… - Journal of the …, 2015 - royalsocietypublishing.org
The development of biomaterials for cardiac tissue engineering (CTE) is challenging,
primarily owing to the requirement of achieving a surface with favourable characteristics that …