Sample preparation and detection methods in point-of-care devices towards future at-home testing

G Adedokun, M Alipanah, ZH Fan - Lab on a Chip, 2024 - pubs.rsc.org
Timely and accurate diagnosis is critical for effective healthcare, yet nearly half the global
population lacks access to basic diagnostics. Point-of-care (POC) testing offers partial …

Advances in point-of-care optical biosensing for underserved populations

N Chaturvedi, A Goncharov, S Tripathy… - TrAC Trends in …, 2024 - Elsevier
Portable optical biosensors have been created over the last 30 years for detecting molecular
and cellular targets. More recently, advances in algorithms, readers, and materials have …

A multiplexed, allele-specific recombinase polymerase amplification assay with lateral flow readout for sickle cell disease detection

MM Chang, ME Natoli, AF Wilkinson, VN Tubman… - Lab on a Chip, 2024 - pubs.rsc.org
Isothermal nucleic acid amplification tests have the potential to improve disease diagnosis at
the point of care, but it remains challenging to develop multiplexed tests that can detect≥ 3 …

A novel tailed primer nucleic acid test for detection of HPV 16, 18 and 45 DNA at the point of care

MM Chang, A Ma, EN Novak, M Barra, KA Kundrod… - Scientific reports, 2023 - nature.com
Cervical cancer is a leading cause of death for women in low-resource settings despite
being preventable through human papillomavirus (HPV) vaccination, early detection, and …

Multi-dimensional microfluidic paper-based analytical devices (μPADs) for noninvasive testing: A review of structural design and applications

T Chen, C Sun, SC Abbas, N Alam, S Qiang, X Tian… - Analytica Chimica …, 2024 - Elsevier
The rapid emergence of microfluidic paper-based devices as point-of-care testing (POCT)
tools for early disease diagnosis and health monitoring, particularly in resource-limited …

Enhancing fuel transport and cell performance by an anodic wedge-shaped channel in a paper-based microfluidic fuel cell

J Wen, D Ye, X Zhu, R Chen, Y Yang, Q Lan… - Journal of Power …, 2024 - Elsevier
Highlights•Wedge-shaped channel is formed by inserting anode between two-layer flow
channel.•The anodic wedge-shaped channel can significantly increase fuel flow …

An Injection Molded SlipChip with Self‐Sampling for Integrated Point‐of‐Care Testing of Human Papilloma Virus

J Zhang, Z Dong, L Xu, X Han, Z Sheng… - Advanced …, 2024 - Wiley Online Library
High‐risk human papillomavirus (HPV) screening is crucial for cervical cancer prevention.
However, laboratory‐based nucleic acid amplification tests (NAATs) require costly …

Advanced technologies towards improved HPV diagnostics

M Bartosik, L Moranova, N Izadi… - Journal of Medical …, 2024 - Wiley Online Library
Persistent infection with high‐risk types of human papillomaviruses (HPV) is a major cause
of cervical cancer, and an important factor in other malignancies, for example, head and …

The Evolving Landscape of Cervical Cancer: Breakthroughs in Screening and Therapy Through Integrating Biotechnology and Artificial Intelligence

R Aswathy, S Sumathi - Molecular Biotechnology, 2024 - Springer
Cervical cancer (CC) continues to be a major worldwide health concern, profoundly
impacting the lives of countless females worldwide. In low-and middle-income countries …

Single-tube four-target lateral flow assay detects human papillomavirus types associated with majority of cervical cancers

M Barra, M Chang, MP Salcedo, K Schmeler… - Analytical …, 2024 - Elsevier
Isothermal nucleic acid amplification methods have many advantages for use at the point of
care. However, there is a lack of multiplexed isothermal amplification tests to detect multiple …