[HTML][HTML] BCR-ABL independent mechanisms of resistance in chronic myeloid leukemia

F Loscocco, G Visani, S Galimberti, A Curti… - Frontiers in …, 2019 - frontiersin.org
Not all chronic myeloid leukemia (CML) patients are cured with tyrosine kinase inhibitors
(TKIs), and a proportion of them develop resistance. Recently, continuous BCR-ABL gene …

[HTML][HTML] MicroRNAs in cancer biology and therapy: current status and perspectives

C Price, J Chen - Genes & diseases, 2014 - Elsevier
The study of a class of small non-coding RNA molecules, named microRNAs (miRNAs), has
advanced our understanding of many of the fundamental processes of cancer biology and …

[HTML][HTML] Long non-coding RNA CCAT1 acts as a competing endogenous RNA to regulate cell growth and differentiation in acute myeloid leukemia

L Chen, W Wang, L Cao, Z Li, X Wang - Molecules and cells, 2016 - Elsevier
Long non-coding RNAs (lncRNAs) are involved in multiple cellular events, as well as in
tumorigenesis. Colon cancer-associated transcript-1 (CCAT1) gene encodes an lncRNA …

[HTML][HTML] Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance

AA Bhat, SN Younes, SS Raza, L Zarif, S Nisar… - Molecular cancer, 2020 - Springer
Early-stage detection of leukemia is a critical determinant for successful treatment of the
disease and can increase the survival rate of leukemia patients. The factors limiting the …

[HTML][HTML] COVID-19 in patients with anemia and haematological malignancies: risk factors, clinical guidelines, and emerging therapeutic approaches

S Kakavandi, B Hajikhani, P Azizi, F Aziziyan… - Cell Communication and …, 2024 - Springer
Extensive research in countries with high sociodemographic indices (SDIs) to date has
shown that coronavirus disease 2019 (COVID-19) may be directly associated with more …

MicroRNAs as haematopoiesis regulators

RB Undi, R Kandi, RK Gutti - Advances in hematology, 2013 - Wiley Online Library
The production of different types of blood cells including their formation, development, and
differentiation is collectively known as haematopoiesis. Blood cells are divided into three …

Regulation of cancer metastasis by cell-free miRNAs

M Alečković, Y Kang - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2015 - Elsevier
MicroRNAs (miRNAs) are integral molecules in the regulation of numerous physiological
cellular processes that have emerged as critical players in cancer initiation and metastatic …

[HTML][HTML] MicroRNA-155 as an inducer of apoptosis and cell differentiation in Acute Myeloid Leukaemia

CA Palma, D Al Sheikha, TK Lim, A Bryant, TT Vu… - Molecular cancer, 2014 - Springer
Background Acute myeloid leukaemia (AML) is characterised by the halt in maturation of
myeloid progenitor cells, combined with uncontrolled proliferation and abnormal survival …

[HTML][HTML] MicroRNAs mediated regulation of MAPK signaling pathways in chronic myeloid leukemia

C Chakraborty, AR Sharma, BC Patra… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Chronic myeloid leukemia (CML) is a severe problem throughout the world and requires
identification of novel targets for its treatment. This multifactorial disease accounts for about …

[HTML][HTML] New insights into the expression profile and function of micro-ribonucleic acid in human spermatozoa

A Salas-Huetos, J Blanco, F Vidal, JM Mercader… - Fertility and sterility, 2014 - Elsevier
Objective To characterize the microRNA (miRNA) expression profile in spermatozoa from
human fertile individuals and their implications in human fertility. Design The expression …