[HTML][HTML] Bis-indole based triazine derivatives: Synthesis, characterization, in vitro β-glucuronidase anti-cancer and anti-bacterial evaluation along with in silico …
The present work described the synthetic procedure adopted for the synthesis of bis-indole-
based triazine derivatives via a series of reactions. All the compounds were synthesized …
based triazine derivatives via a series of reactions. All the compounds were synthesized …
Imidazopyridine-based thiazole derivatives as potential antidiabetic agents: synthesis, in vitro bioactivity, and in silico molecular modeling approach
A new series of thiazole derivatives (4a-p) incorporating imidazopyridine moiety was
synthesized and assessed for their in vitro potential α-glucosidase potency using acarbose …
synthesized and assessed for their in vitro potential α-glucosidase potency using acarbose …
[HTML][HTML] Exploring effective diagnosis of Alzheimer disease: Experimental and computational analysis of hybrid benzimidazole based thiazolidinone derivatives
The current study was conducted to establish a unique synthetic route for the synthesis of
varied substituted benzimidazole derived thiazole base thiazolidinone derivatives by using …
varied substituted benzimidazole derived thiazole base thiazolidinone derivatives by using …
Synthesis, crystal structure, Hirshfeld surface analysis, DFT and antihyperglycemic activity of 9-allyl-2, 3, 9, 10a-tetrahydrobenzo [b] cyclopenta [e][1, 4] diazepin-10 …
In this work, a novel benzodiazepine-2-one derivative (4) was synthesized by N-allylation of
cyclopenta [e][1, 5] benzodiazepine-2-one. The chemical structure of the target compound …
cyclopenta [e][1, 5] benzodiazepine-2-one. The chemical structure of the target compound …
Recent Developments in 1, 2, 3‐Triazole Based α‐Glucosidase Inhibitors: Design Strategies, Structure‐Activity Relationship and Mechanistic Insights
Diabetes mellitus is a chronic and most prevalent metabolic disorder affecting 422 million
the people worldwide and causing life‐threatening associated conditions including …
the people worldwide and causing life‐threatening associated conditions including …
Indole 3-heterocyclic derivative: a potential antioxidant, antidiabetic agent and their docking study on alpha amylase
S Jagadeesan, S Karpagam, A Noor, R Basu - Journal of Molecular …, 2023 - Elsevier
Abstract α-Amylase enzymes play a crucial role in breaking down starch molecules into
simple sugar units that are easily absorbed into the bloodstream, resulting in a sudden …
simple sugar units that are easily absorbed into the bloodstream, resulting in a sudden …
[HTML][HTML] Blood indices of omega-3 and omega-6 polyunsaturated fatty acids are altered in hyperglycemia
Polyunsaturated fatty acids (PUFAs) may favorably influence the risk and clinical course of
diabetes mellitus (DM). In particular, eicosapentaenoic acid (EPA), docosahexaenoic acid …
diabetes mellitus (DM). In particular, eicosapentaenoic acid (EPA), docosahexaenoic acid …
Design, Synthesis, and Molecular Docking Studies of Integrated Benzylidenethiazolidine‐2,4‐Dione and Thieno[2,3‐d]pyrimidine‐6‐Carboxylate Derivatives as …
B Nagaraju, M Rajeswari, N Vedasree, CA Rao… - …, 2023 - Wiley Online Library
The present work describes the synthesis of new series of 5‐arylidene‐thiazolidine‐2, 4‐
dione, thieno [2, 3‐d] pyrimidine‐6‐carboxylate derivatives 9 a–o. A variety of spectroscopic …
dione, thieno [2, 3‐d] pyrimidine‐6‐carboxylate derivatives 9 a–o. A variety of spectroscopic …
α‐Amylase Inhibitors Based on Thiazolidinone Skeleton: A Promising Approach in Diabetes Management
Thiazolidinone scaffold has become a promising scaffold when it comes to therapeutic
importance, and researchers are quite interested in it because of its wide range of …
importance, and researchers are quite interested in it because of its wide range of …
Evaluation of acute oral toxicity, anti-diabetic and antioxidant effects of Aloe vera flowers extract
NMIM Elkomy, A El-Shaibany, GM Elnagar… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Aloe vera (L.) Burm. f. is widely used in various traditional
systems of medicine worldwide. Since over 5000 years ago, several cultures have used A …
systems of medicine worldwide. Since over 5000 years ago, several cultures have used A …