The prevalence of obesity has tripled over the past four decades, imposing an enormous
burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset …

There is a genetic component to human obesity that accounts for 40% to 50% of the
variability in body weight status but that is lower among normal weight individuals (about …

Abstract Here the Human Pangenome Reference Consortium presents a first draft of the
human pangenome reference. The pangenome contains 47 phased, diploid assemblies …

In recent years, research in behavioral medicine has become increasingly focused on
understanding how chronic and acute exposure to stress impacts health outcomes. During …

In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …

The specific metabolic contribution of consuming different energy-yielding macronutrients
(namely, carbohydrates, protein and lipids) to obesity is a matter of active debate. In this …

Dietary carbohydrates: role of quality and quantity in chronic disease Page 1 the bmj | BMJ
2018;361:k2340 | doi: 10.1136/bmj.k2340 1 Science and PoliticS of nutrition Dietary …

Genetic predisposition to obesity presents a paradox: how do genetic variants with a
detrimental impact on human health persist through evolutionary time? Numerous …

The global rise in the prevalence of obesity and associated co-morbidities such as type 2
diabetes, cardiovascular disease, and cancer represents a major public health concern. The …

The discovery of genetic variation and the assembly of genome sequences are both
inextricably linked to advances in DNA-sequencing technology. Short-read massively …