[HTML][HTML] In silico vaccine design: A tutorial in immunoinformatics
DD Martinelli - Healthcare Analytics, 2022 - Elsevier
Immunoinformatics, as a discipline, concerns the application of computational systems to
study the immune system. Recently, the principles of reverse vaccinology have united with …
study the immune system. Recently, the principles of reverse vaccinology have united with …
Immunoinformatics design of a novel epitope-based vaccine candidate against dengue virus
AO Fadaka, NRS Sibuyi, DR Martin, M Goboza… - Scientific reports, 2021 - nature.com
Dengue poses a global health threat, which will persist without therapeutic intervention.
Immunity induced by exposure to one serotype does not confer long-term protection against …
Immunity induced by exposure to one serotype does not confer long-term protection against …
Clostridium septicum: A review in the light of alpha-toxin and development of vaccines
MLF Alves, MRA Ferreira, RA Donassolo… - Vaccine, 2021 - Elsevier
Clostridium septicum (CS) is a pathogen that can cause the death of animals in livestock
worldwide through its main virulence factor, alpha-toxin (ATX). The aspects involved in …
worldwide through its main virulence factor, alpha-toxin (ATX). The aspects involved in …
Design of a novel multi-epitope vaccine candidate against hepatitis C virus using structural and nonstructural proteins: An immunoinformatics approach
Hepatitis C virus (HCV) infects the liver and causes chronic infection. Several mutations in
the viral genome have been associated with drug resistance development. Currently, there …
the viral genome have been associated with drug resistance development. Currently, there …
Integrated core proteomics, subtractive proteomics, and immunoinformatics investigation to unveil a potential multi-epitope vaccine against schistosomiasis
Schistosomiasis is a parasitic infection that causes considerable morbidity and mortality in
the world. Infections of parasitic blood flukes, known as schistosomes, cause the disease …
the world. Infections of parasitic blood flukes, known as schistosomes, cause the disease …
Multi-epitope vaccine against SARS-CoV-2 applying immunoinformatics and molecular dynamics simulation approaches
Jyotisha, S Singh, IA Qureshi - Journal of Biomolecular Structure …, 2022 - Taylor & Francis
Abstract COVID-19, caused by SARS-CoV-2, is severe respiratory illnesses leading to
millions of deaths worldwide in very short span. The high case fatality rate and the lack of …
millions of deaths worldwide in very short span. The high case fatality rate and the lack of …
Combining Phage Display Technology with In Silico-Designed Epitope Vaccine to Elicit Robust Antibody Responses against Emerging Pathogen Tilapia Lake Virus
YM Gong, XF Wei, YY Zheng, Y Li, Q Yu, PF Li… - Journal of …, 2023 - Am Soc Microbiol
Antigen epitope identification is a critical step in the vaccine development process and is a
momentous cornerstone for the development of safe and efficient epitope vaccines. In …
momentous cornerstone for the development of safe and efficient epitope vaccines. In …
An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani …
Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
Computational Modeling, High-Level Soluble Expression and In Vitro Cytotoxicity Assessment of Recombinant Pseudomonas aeruginosa Azurin: A Promising Anti …
Azurin is a natural protein produced by Pseudomonas aeruginosa that exhibits potential anti-
tumor, anti-HIV, and anti-parasitic properties. The current study aimed to investigate the …
tumor, anti-HIV, and anti-parasitic properties. The current study aimed to investigate the …
[HTML][HTML] Proteome based mapping and reverse vaccinology techniques to contrive multi-epitope based subunit vaccine (MEBSV) against Streptococcus pyogenes
Streptococcus pyogenes is a root cause of human infection like pharyngitis, tonsillitis, scarlet
fever, impetigo, and respiratory tract infections. About 11 million individuals in the US suffer …
fever, impetigo, and respiratory tract infections. About 11 million individuals in the US suffer …