Lab-on-a-chip devices for point-of-care medical diagnostics

S Arshavsky-Graham, E Segal - Microfluidics in Biotechnology, 2020 - Springer
Abstract The recent coronavirus (COVID-19) pandemic has underscored the need to move
from traditional lab-centralized diagnostics to point-of-care (PoC) settings. Lab-on-a-chip …

Optomagnetic biosensors: Volumetric sensing based on magnetic actuation-induced optical modulations

X Xiao, C Yuan, T Li, J Fock, P Svedlindh… - Biosensors and …, 2022 - Elsevier
In comparison to alternative nanomaterials, magnetic micron/nano-sized particles show
unique advantages, eg, easy manipulation, stable signal, and high contrast. By applying …

[HTML][HTML] Magnetic polymers for magnetophoretic separation in microfluidic devices

L Descamps, D Le Roy, C Tomba, A Deman - Magnetochemistry, 2021 - mdpi.com
Magnetophoresis offers many advantages for manipulating magnetic targets in
microsystems. The integration of micro-flux concentrators and micro-magnets allows …

[HTML][HTML] Nucleic acid amplification strategies for volume-amplified magnetic nanoparticle detection assay

Z Huang, J Li, H Zhong, B Tian - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Magnetic nanoparticles (MNPs) can be quantified based on their magnetic relaxation
properties by volumetric magnetic biosensing strategies, for example, alternating current …

[HTML][HTML] Self-assembled permanent micro-magnets in a polymer-based microfluidic device for magnetic cell sorting

L Descamps, MC Audry, J Howard, S Mekkaoui… - Cells, 2021 - mdpi.com
Magnetophoresis-based microfluidic devices offer simple and reliable manipulation of micro-
scale objects and provide a large panel of applications, from selective trapping to high …

The review of Lab‐on‐PCB for biomedical application

W Zhao, S Tian, L Huang, K Liu, L Dong - Electrophoresis, 2020 - Wiley Online Library
Prevention of infectious diseases, diagnosis of diseases, and determination of treatment
options all rely on biosensors to detect and analyze biomarkers, which are usually divided …

[HTML][HTML] Microparticle-based detection of viruses

B Khanthaphixay, L Wu, JY Yoon - Biosensors, 2023 - mdpi.com
Surveillance of viral pathogens in both point-of-care and clinical settings is imperative to
preventing the widespread propagation of disease—undetected viral outbreaks can pose …

[HTML][HTML] Nucleic acid-based sensing techniques for diagnostics and surveillance of influenza

SJ Courtney, ZR Stromberg, JZ Kubicek-Sutherland - Biosensors, 2021 - mdpi.com
Influenza virus poses a threat to global health by causing seasonal outbreaks as well as
three pandemics in the 20th century. In humans, disease is primarily caused by influenza A …

[HTML][HTML] Rolling circle amplification as a universal method for the analysis of a wide range of biological targets

RR Garafutdinov, AR Sakhabutdinova… - Russian Journal of …, 2021 - Springer
Detection and quantification of biotargets are important analytical tasks, which are solved
using a wide range of various methods. In recent years, methods based on the isothermal …

Nicking-assisted on-loop and off-loop enzymatic cascade amplification for optomagnetic detection of a highly conserved dengue virus sequence

B Tian, J Fock, GAS Minero, MF Hansen - Biosensors and Bioelectronics, 2020 - Elsevier
Applications of conventional linear ligation-rolling circle amplification (RCA) are restricted by
the sophisticated operation steps and unsatisfactory picomolar-level detection limits. We …