[HTML][HTML] Pharmacological treatment strategies of pterygium: drugs, biologics, and novel natural products
SS Baheran, RG Alany, S Schwikkard, W Muen… - Drug Discovery …, 2023 - Elsevier
Pterygium is a fibrovascular tissue growth invading the cornea. Adjunctive treatment post-
surgery includes conventional immunosuppressants as well as antiviral drugs. The use of …
surgery includes conventional immunosuppressants as well as antiviral drugs. The use of …
Recent Advances in the Metal Catalyzed Asymmetric Alkene Hydrogenation of Cyclic Conjugated Carbonyl Compounds
M Tan, BBC Peters, P Andersson… - Organic Chemistry …, 2024 - pubs.rsc.org
The transition metal-catalyzed asymmetric hydrogenation of carbon–carbon double bonds is
recognized as one of the most straightforward methods for the preparation of stereopure …
recognized as one of the most straightforward methods for the preparation of stereopure …
Spiro-Flavonoids in Nature: A Critical Review of Structural Diversity and Bioactivity
Ł Pecio, S Pecio, T Mroczek, W Oleszek - Molecules, 2023 - mdpi.com
Based on the literature data from 1973 to 2022, this work summarizes reports on spiro-
flavonoids with a spiro-carbon at the center of their structure and how this affects their …
flavonoids with a spiro-carbon at the center of their structure and how this affects their …
Discovering the potential of natural antioxidants in age-related macular degeneration: a review
Age-related macular degeneration (AMD) is a multifactorial disease associated with
anatomical changes in the inner retina. Despite tremendous advances in clinical care, there …
anatomical changes in the inner retina. Despite tremendous advances in clinical care, there …
A comprehensive review on chemotaxonomic and phytochemical aspects of homoisoflavonoids, as rare flavonoid derivatives
J Mottaghipisheh, H Stuppner - International Journal of Molecular …, 2021 - mdpi.com
Homoisoflavonoids (3-benzylidene-4-chromanones) are considered as an infrequent
flavonoid class, possessing multi-beneficial bioactivities. The present study gives an …
flavonoid class, possessing multi-beneficial bioactivities. The present study gives an …
Design, synthesis and evaluation of dihydro-1H-indene derivatives as novel tubulin polymerisation inhibitors with anti-angiogenic and antitumor potency
S Xu, Y Sun, P Wang, Y Tan, L Shi… - Journal of Enzyme …, 2023 - Taylor & Francis
Angiogenesis plays an important role in tumour generation and progression, which is used
to supply nutrients and metastasis. Herein, a series of novel dihydro-1 H-indene derivatives …
to supply nutrients and metastasis. Herein, a series of novel dihydro-1 H-indene derivatives …
Exploring the Antiangiogenic and Anti-Inflammatory Potential of Homoisoflavonoids: Target Identification Using Biotin Probes
Chemical proteomics using biotin probes of natural products have significantly advanced
our understanding of molecular targets and therapeutic potential. This review highlights …
our understanding of molecular targets and therapeutic potential. This review highlights …
Enantioselective synthesis of homoisoflavanones by asymmetric transfer hydrogenation and their biological evaluation for antiangiogenic activity
M Heo, B Lee, K Sishtla, X Fei, S Lee… - The Journal of …, 2019 - ACS Publications
Neovascular eye diseases are a major cause of blindness. Excessive angiogenesis is a
feature of several conditions, including wet age-related macular degeneration, proliferative …
feature of several conditions, including wet age-related macular degeneration, proliferative …
N‐Heterocyclic Carbene‐Catalyzed Enantioselective Intramolecular Annulations to Construct Benzo‐Fused Pyranones with Quaternary Stereocenter
K Dzieszkowski, Z Rafiński - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
A highly enantioselective intramolecular NHC‐catalyzed approach for the synthesis of
benzo‐fused pyranones bearing quaternary stereocenter is described. The developed …
benzo‐fused pyranones bearing quaternary stereocenter is described. The developed …
Isolation and characterization of dihydrohomoisoflavonoids from Portulaca oleracea L.
J Liu, H Wang, H Shao, J Sun, C Dong, R Chen, J Kang - Phytochemistry, 2024 - Elsevier
Abstract Eight pairs of dihydrohomoisoflavonoids (1− 8), including four pairs of enantiomeric
aglycones [(R, S)-portulacanones B (1) and C (2) and (R, S)-oleracones C (3) and Q (4)] and …
aglycones [(R, S)-portulacanones B (1) and C (2) and (R, S)-oleracones C (3) and Q (4)] and …