In recent years there has been enormous interest in researching oxidative stress. Reactive
oxygen species (ROS) are derived from the metabolism of oxygen as by-products of cell …

High ambient temperatures are a critical challenge in the poultry industry which is a key
producer of the animal-based food. To evaluate heat stress levels, various parameters have …

The complexes of the electron transport chain associate into large macromolecular
assemblies, which are believed to facilitate efficient electron flow. We have identified a …

The first member of the uncoupling protein (UCP) family, brown adipose tissue uncoupling
protein 1 (UCP1), was identified in 1976. Twenty years later, two closely related proteins …

Acute heat stress (34° C for 18 h) resulted in increased levels of reactive oxygen species
(ROS) in mitochondria isolated from the skeletal muscle of broilers. This occurred when …

Reactive oxygen species-induced damage of cells and molecules is one of the mechanisms
responsible for the decline in an animal's performance due to heat stress. Mitochondria are …

The mitochondrion is a major organelle contributing to energy metabolism but also a main
site of ROS (reactive oxygen species) production. LPS (lipopolysaccharide)-induced ROS …

In mammals the two proteins UCP2 and UCP3 are highly similar to the mitochondrial
uncoupling protein found in the brown adipose tissue (UCP1). Accordingly, it was proposed …

We used the fruit fly Drosophila melanogaster to test the effects of feeding the superoxide
dismutase (SOD) mimetic drugs Euk-8 and-134 and the mitochondria-targeted mitoquinone …

Converting food to chemical energy (ATP) that is usable by cells is a principal requirement to
sustain life. The rate of ATP production has to be sufficient for housekeeping functions, such …