Fungal proteases as emerging biocatalysts to meet the current challenges and recent developments in biomedical therapies: an updated review
With the increasing world population, demand for industrialization has also increased to
fulfill humans' living standards. Fungi are considered a source of essential constituents to …
fulfill humans' living standards. Fungi are considered a source of essential constituents to …
Matrix metalloproteinase contribution in management of cancer proliferation, metastasis and drug targeting
NM Abdel-Hamid, SA Abass - Molecular biology reports, 2021 - Springer
Matrix metalloproteinases (MMPs) or matrixins, are members of a zinc-dependent
endopeptidase family. They cause remodeling of the extracellular matrix (ECM) leading to …
endopeptidase family. They cause remodeling of the extracellular matrix (ECM) leading to …
Recent advances in nanoparticle-based cancer treatment: a review
The advent and subsequent development of nanotechnology in the past few years have
been a boon to the healthcare industry and especially in cancer therapy. Cancer, as it is …
been a boon to the healthcare industry and especially in cancer therapy. Cancer, as it is …
Cathepsin D—managing the delicate balance
O Mijanovic, AI Petushkova, A Brankovic, B Turk… - Pharmaceutics, 2021 - mdpi.com
Lysosomal proteases play a crucial role in maintaining cell homeostasis. Human cathepsin
D manages protein turnover degrading misfolded and aggregated proteins and favors …
D manages protein turnover degrading misfolded and aggregated proteins and favors …
The roles of proteases in prostate cancer
H Koistinen, RM Kovanen, MD Hollenberg… - IUBMB …, 2023 - Wiley Online Library
Since the proposition of the pro‐invasive activity of proteolytic enzymes over 70 years ago,
several roles for proteases in cancer progression have been established. About half of the …
several roles for proteases in cancer progression have been established. About half of the …
Drug delivery strategies for the treatment of pancreatic cancer
Pancreatic cancer is fast becoming a global menace and it is projected to be the second
leading cause of cancer-related death by 2030. Pancreatic adenocarcinomas, which …
leading cause of cancer-related death by 2030. Pancreatic adenocarcinomas, which …
The interplay between gut microbiota and oral medications and its impact on advancing precision medicine
Trillions of diverse microbes reside in the gut and are deeply interwoven with the human
physiological process, from food digestion, immune system maturation, and fighting invading …
physiological process, from food digestion, immune system maturation, and fighting invading …
High‐Throughput Cellular Heterogeneity Analysis in Cell Migration at the Single‐Cell Level
Cancer cell migration represents an essential step toward metastasis and cancer deaths.
However, conventional drug discovery focuses on cytotoxic and growth‐inhibiting …
However, conventional drug discovery focuses on cytotoxic and growth‐inhibiting …
[HTML][HTML] Exploring the nutritional and health benefits of pulses from the Indian Himalayan region: A glimpse into the region's rich agricultural heritage
Pulses have been consumed worldwide for over 10 centuries and are currently among the
most widely used foods. They are not economically important, but also nutritionally …
most widely used foods. They are not economically important, but also nutritionally …
Regulation of peptidase activity beyond the active site in human health and disease
A Obaha, M Novinec - International journal of molecular sciences, 2023 - mdpi.com
This comprehensive review addresses the intricate and multifaceted regulation of peptidase
activity in human health and disease, providing a comprehensive investigation that extends …
activity in human health and disease, providing a comprehensive investigation that extends …