Childhood asthma is an umbrella of multifactorial diseases with similar clinical features such
as mast cell and eosinophil infiltration causing airway hyper responsiveness, inflammation …

The respiratory epithelium constitutes the physical barrier between the human body and the
environment, thus providing functional and immunological protection. It is often exposed to …

Asthma is a global health problem with increasing prevalence. The airway epithelium is the
initial barrier against inhaled noxious agents or aeroallergens. In asthma, the airway …

Allergic asthma is a prominent disease especially during childhood. Indoor allergens, in
general, and particularly house dust mites (HDM) are the most prevalent sensitizers …

Background Asthma is a common complex chronic, inflammatory polygenic disease with
heterogeneous manifestations, affecting individuals of all age groups and posing an …

Over the last few years, a significant progress has been made in understanding the role of a
disintegrin and metalloproteinase 33 (ADAM33) in asthma. The previous observations for …

Asthma is a complex chronic respiratory disease characterized by airway
hyperresponsiveness, inflammation, and obstruction. Many genes have been identified as …

Abstract Background Coronavirus Disease of 2019 (COVID-19) is a contagious disease
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients had …

Objective: A disintegrin and metalloproteinase 33 (ADAM33) gene has been considered as
an asthma susceptibility gene due to its possible role in airway remodeling, abnormal cell …

A disintegrin and metalloproteinase 33 (ADAM33) has been identified as a susceptibility
gene for asthma, but details of the causality are not fully understood. We hypothesize that …