A considerable body of evidence exists suggesting that androgen deficiency contributes to
the onset, progression, or both of cardiovascular disease (CVD). The aim of this review is to …

Abstract Introduction Testosterone (T) deficiency (TD; hypogonadism) has deleterious effects
on men's health; negatively affects glycometabolic and cardiometabolic functions, body …

The relationship between androgen deficiency and atherosclerosis is complex, poorly
understood, and remains controversial. The aim of this review is to evaluate the data in the …

Testosterone and its metabolite, 5α-dihydrotestosterone are critical metabolic and vascular
hormones, which regulate a host of biochemical pathways including carbohydrate, lipid and …

Introduction Numerous clinical series have reported an association between 5‐alpha‐
reductase inhibitors (5ARIs) and sexual dysfunction, but there are limited preclinical data …

Androgens are essential for development, growth, and maintenance of penile structure, and
regulate erectile physiology by multiple mechanisms. Here we provide a concise overview of …

Phosphodiesterase type 5 inhibitors (PDE5Is) are the drug of choice for medical
management of erectile dysfunction (ED). On-demand PDE5Is have an overall efficacy of 60 …

Erectile dysfunction (ED) affects approximately half of men during middle age. Erectile
dysfunction is often an early symptom of systemic vascular disease, which may precipitate …

The incidence of erectile dysfunction (ED) increases with age and cardiovascular disease
risk factors, such as hypertension, hyperlipidemia, insulin resistance, obesity, and diabetes …

Despite several studies showing an inverse correlation of total testosterone with endothelial
damage, the effect of testosterone replacement therapy (TTh) on endothelial function has …