TNFR1 and TNFR2 in the control of the life and death balance of macrophages
H Wajant, D Siegmund - Frontiers in cell and developmental biology, 2019 - frontiersin.org
Macrophages stand in the first line of defense against a variety of pathogens but are also
involved in the maintenance of tissue homeostasis. To fulfill their functions macrophages …
involved in the maintenance of tissue homeostasis. To fulfill their functions macrophages …
PANoptosis: Mechanisms, biology, and role in disease
X Sun, Y Yang, X Meng, J Li, X Liu… - Immunological …, 2024 - Wiley Online Library
Cell death can be executed through distinct subroutines. PANoptosis is a unique
inflammatory cell death modality involving the interactions between pyroptosis, apoptosis …
inflammatory cell death modality involving the interactions between pyroptosis, apoptosis …
A bibliometric analysis of pyroptosis from 2001 to 2021
D Ma, B Yang, B Guan, L Song, Q Liu, Y Fan… - Frontiers in …, 2021 - frontiersin.org
Background Pyroptosis is a new programmed cell death discovered in recent years.
Pyroptosis plays an important role in various diseases. Nevertheless, there are few …
Pyroptosis plays an important role in various diseases. Nevertheless, there are few …
WTAP-mediated N6-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy
J Lan, B Xu, X Shi, Q Pan, Q Tao - Cellular & Molecular Biology Letters, 2022 - Springer
Background Diabetic nephropathy (DN) is prevalent in patients with diabetes. N 6-
methyladenosine (m6A) methylation has been found to cause modification of nucleotide …
methyladenosine (m6A) methylation has been found to cause modification of nucleotide …
Pyroptosis, and its role in central nervous system disease
Pyroptosis is an inflammatory form of cell death executed by transmembrane pore-forming
proteins known as gasdermins and can be activated in an inflammasome-dependent or …
proteins known as gasdermins and can be activated in an inflammasome-dependent or …
Current translational potential and underlying molecular mechanisms of necroptosis
Cell death has a fundamental impact on the evolution of degenerative disorders,
autoimmune processes, inflammatory diseases, tumor formation and immune surveillance …
autoimmune processes, inflammatory diseases, tumor formation and immune surveillance …
Nod-like receptors: critical intracellular sensors for host protection and cell death in microbial and parasitic infections
AO Babamale, ST Chen - International journal of molecular sciences, 2021 - mdpi.com
Cell death is an essential immunological apparatus of host defense, but dysregulation of
mutually inclusive cell deaths poses severe threats during microbial and parasitic infections …
mutually inclusive cell deaths poses severe threats during microbial and parasitic infections …
Transcriptional regulation of inflammasomes
M Cornut, E Bourdonnay, T Henry - International journal of molecular …, 2020 - mdpi.com
Inflammasomes are multimolecular complexes with potent inflammatory activity. As such,
their activity is tightly regulated at the transcriptional and post-transcriptional levels. In this …
their activity is tightly regulated at the transcriptional and post-transcriptional levels. In this …
Pyroptosis: A road to next-generation cancer immunotherapy
Y Fang, Y Tang, B Huang - Seminars in Immunology, 2023 - Elsevier
The goal of cancer immunotherapy is to clear tumor cells by activating antitumor immunity,
especially by mobilizing tumor-reactive CD8+ T cells. Pyroptosis, programmed lytic cell …
especially by mobilizing tumor-reactive CD8+ T cells. Pyroptosis, programmed lytic cell …
Redox biology of regulated cell death in cancer: A focus on necroptosis and ferroptosis
Redox changes and generation of reactive oxygen species (ROS) are part of normal cell
metabolism. While low ROS levels are implicated in cellular signaling pathways necessary …
metabolism. While low ROS levels are implicated in cellular signaling pathways necessary …