WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndrome

HG Kim, JW Ahn, I Kurth, R Ullmann, HT Kim… - The American Journal of …, 2010 - cell.com
By defining the chromosomal breakpoint of a balanced t (10; 12) translocation from a subject
with Kallmann syndrome and scanning genes in its vicinity in unrelated hypogonadal …

Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis

Z Hu, J Zhang, Q Zhang - Autophagy, 2011 - Taylor & Francis
The implications of autophagy-related genes in serious neural degenerative diseases have
been well documented. However, the functions and regulation of the family genes in …

Targeted knockout of a chemokine-like gene increases anxiety and fear responses

JH Choi, YM Jeong, S Kim, B Lee… - Proceedings of the …, 2018 - National Acad Sciences
Emotional responses, such as fear and anxiety, are fundamentally important behavioral
phenomena with strong fitness components in most animal species. Anxiety-related …

Inhibition of MKK7–JNK by the TOR signaling pathway regulator-like protein contributes to resistance of HCC cells to TRAIL-induced apoptosis

IS Song, SY Jun, HJ Na, HT Kim, SY Jung, GH Ha… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: The TOR signaling pathway regulator-like (TIPRL) protein, the
mammalian ortholog of yeast TIP41, was identified in an expression profiling screen for …

The microcephaly gene aspm is involved in brain development in zebrafish

HT Kim, MS Lee, JH Choi, JY Jung, DG Ahn… - Biochemical and …, 2011 - Elsevier
MCPH is a neurodevelopmental disorder characterized by a global reduction in cerebral
cortical volume. Homozygous mutation of the MCPH5 gene, also known as ASPM, is the …

Optogenetic manipulation of olfactory responses in transgenic zebrafish: A neurobiological and behavioral study

YM Jeong, TI Choi, KS Hwang, JS Lee… - International Journal of …, 2021 - mdpi.com
Olfaction is an important neural system for survival and fundamental behaviors such as
predator avoidance, food finding, memory formation, reproduction, and social …

Cytoarchitectonic and neurochemical differentiation of the visual system in ethanol-induced cyclopic zebrafish larvae

A Santos-Ledo, FJ Arenzana, A Porteros, J Lara… - Neurotoxicology and …, 2011 - Elsevier
Embryonic exposure to ethanol leads to malformations such as cyclopia. Cyclopic embryos
present fused eyes and lack of the ventral specification of the brain, with physiological and …

Cancer‐upregulated gene 2 (CUG2) overexpression induces apoptosis in SKOV‐3 cells

S Lee, W Koh, HT Kim, CH Kim… - Cell Biochemistry and …, 2010 - Wiley Online Library
Abstract Cancer‐upregulated gene 2 (CUG2) was originally identified as a potential
oncogene commonly up‐regulated in various human cancers. Recently, CUG2 was also …

Characterization of a novel primary culture system of adult zebrafish brainstem cells

A Tapanes-Castillo, FS Shabazz, MY Mboge… - Journal of neuroscience …, 2014 - Elsevier
Adult zebrafish (Danio rerio) have a remarkable ability to restore function after an injury to
the brain or spinal cord. The molecular and cellular mechanisms underlying this …

Cug2 is essential for normal mitotic control and CNS development in zebrafish

HT Kim, JH So, SH Jung, DG Ahn, W Koh… - BMC developmental …, 2011 - Springer
Background We recently identified a novel oncogene, Cancer-upregulated gene 2 (CUG2),
which is essential for kinetochore formation and promotes tumorigenesis in mammalian …