Pleiotropic and adverse effects of statins—do epigenetics play a role?
SC Allen, CDS Mamotte - Journal of Pharmacology and Experimental …, 2017 - ASPET
Statins are widely used to prevent major cardiovascular events by lowering serum
cholesterol. There is evidence that statins have pleiotropic effects—that is, cholesterol …
cholesterol. There is evidence that statins have pleiotropic effects—that is, cholesterol …
Statins: Epidrugs with effects on endothelial health?
N Mohammadzadeh, F Montecucco… - European Journal of …, 2020 - Wiley Online Library
Background Epigenetic events involving the methylation of CpG cites in DNA, histone
modifications and noncoding RNAs correlated with many essential processes in human …
modifications and noncoding RNAs correlated with many essential processes in human …
SIRT1 and SIRT7 expression in adipose tissues of obese and normal-weight individuals is regulated by microRNAs but not by methylation status
A Kurylowicz, M Owczarz, J Polosak, MI Jonas… - International Journal of …, 2016 - nature.com
Results: SIRT1 mRNA levels were lower in adipose tissues of obese patients than of normal-
weight controls (VAT: P= 0.0002, SAT: P= 0.008). In contrast, expression of SIRT7 was …
weight controls (VAT: P= 0.0002, SAT: P= 0.008). In contrast, expression of SIRT7 was …
[HTML][HTML] The anti-atherogenic effects of berberine on foam cell formation are mediated through the upregulation of sirtuin 1
L Chi, L Peng, N Pan, X Hu… - … journal of molecular …, 2014 - spandidos-publications.com
Berberine (BBR) is a botanical alkaloid that has been reported to have effects in
cardiovascular diseases; however, the mechanisms involved are not yet fully understood. In …
cardiovascular diseases; however, the mechanisms involved are not yet fully understood. In …
Simvastatin preconditioning confers neuroprotection against hypoxia-ischemia induced brain damage in neonatal rats via autophagy and silent information regulator 1 …
S Carloni, W Balduini - Experimental Neurology, 2020 - Elsevier
Previous studies have shown that simvastatin (Sim) has neuroprotective effects in a
neonatal model of hypoxia-ischemia (HI)-induced brain injury when administered before but …
neonatal model of hypoxia-ischemia (HI)-induced brain injury when administered before but …
阿托伐他汀联合肠溶阿司匹林对颈动脉粥样硬化患者斑块稳定性及脑血管事件的影响
冯欣， 黄晓飞， 邹达良， 黎罗明， 李华文， 周映彤 - 当代医学, 2016 - cqvip.com
目的研究并探讨阿托伐他汀联合肠溶阿司匹林对颈动脉粥样硬化患者的斑块的稳定性以及脑
血管事件发生情况的影响. 方法选取100 例颈动脉粥样硬化患者作为研究对象 …
血管事件发生情况的影响. 方法选取100 例颈动脉粥样硬化患者作为研究对象 …
冠心病常用药物的抗炎作用
杨海平， 孔一慧， 李为民 - 国际心血管病杂志, 2015 - cqvip.com
冠心病常用药物的抗炎作用-[维普官方网站]-www.cqvip.com-维普网 我的维普 购物车 充值 客服
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首页 | 期刊大全 | 文献分类 | 优先出版 | 论文检测 | 论文选题 | 在线分享 | 会议平台 | 学术机构 您的 …
重视老年钙化性主动脉瓣狭窄的防治研究
沈文锦 - 心脏杂志, 2014 - cqvip.com
钙化性主动脉瓣狭窄(CAVS) 是老年人的多发病, 由于其无症状期漫长, 先前一直被认为是“良性
的” 被动性老年退变现象. 新近研究发现, CAVS 的病变实际上是主动的发展过程 …
的” 被动性老年退变现象. 新近研究发现, CAVS 的病变实际上是主动的发展过程 …
An emerging topic on obesity, arterial endothelial function and thrombolysis
K Abe - Journal of Stroke and Cerebrovascular Diseases, 2012 - strokejournal.org
In this volume of Journal of Stroke and Cerebrovascular Diseases, Deguchi et al. report that
obesity may adversely affect recanalization for acute stroke patients after intravenous rt-PA …
obesity may adversely affect recanalization for acute stroke patients after intravenous rt-PA …
强化他汀联合氨氯地平治疗冠状动脉慢血流的临床研究
黎叶飞， 卢辉和， 盛臻强， 郑扣龙 - 中国医学前沿杂志: 电子版, 2015 - cqvip.com
目的本研究旨在观察强化阿托伐他汀联合氨氯地平治疗冠状动脉慢血流的临床效果并探讨可能
的机制. 方法将诊断为冠状动脉慢血流患者分为干预组(36 例) 和对照组(32 例) …
的机制. 方法将诊断为冠状动脉慢血流患者分为干预组(36 例) 和对照组(32 例) …