Acute graft-versus-host disease (GVHD) is a common immune complication that can occur
after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a major …

Over the past 5 years, many novel approaches to early diagnosis, prevention, and treatment
of acute graft-versus-host disease (aGVHD) have been translated from the bench to the …

A joint working group established by the H aemato‐oncology subgroup of the B ritish C
ommittee for S tandards in H aematology (BCSH) and the B ritish S ociety for B one M arrow …

Background The bacterial microflora aggravates graft-versus-host-disease (GvHD) after
allogeneic stem cell transplantation, but the underlying mechanisms of manifestations of …

Abstract Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, play an important
role in the maintenance of peripheral tolerance. We explored the role of PD-1 ligands in …

A major barrier to successful use of allogeneic hematopoietic cell transplantation is acute
graft-versus-host disease (aGVHD), a devastating condition that arises when donor T cells …

Radiological imaging is an integral component of cancer care, including diagnosis, staging,
and treatment response monitoring. It contains rich information about tumor phenotypes that …

T cell activation is an energy-demanding process fueled by increased glucose consumption
and accompanied by upregulation of the insulin receptor (INSR). In this article, we report that …

For several decades, it has been known that T‐cell activation in vitro leads to increased
glycolytic metabolism that fuels proliferation and effector function. Recently, this simple …

In situ cancer vaccines are under active clinical investigation, given their reported ability to
eradicate both local and disseminated malignancies. Intratumoral vaccine administration is …