In this study, we focused on innovative approaches to improve drug administration in oral
pathology, especially by transmucosal and transdermal pathways. These improvements …

Oral leukoplakia is the most frequent and potentially malignant lesion of the oral cavity.
Although dysplasia grading remains the main factor for risk assessment, challenges persist …

Oral squamous cell carcinoma (OSCC) is considered the most common type of head and
neck squamous cell carcinoma (HNSCC) as it holds 90% of HNSCC cases that arise from …

Tumorigenesis is a multistep process, with oncogenic mutations in a normal cell conferring
clonal advantage as the initial event. However, despite pervasive somatic mutations and …

The introduction of immune checkpoint inhibitors (ICIs) to oncological care has transformed
the management of various malignancies, including head and neck squamous cell …

Immunotherapy has developed into an important modality of modern cancer treatment.
Unfortunately, checkpoint inhibitor immunotherapies are currently delivered systemically …

Abstract Purpose of Review This review aims to provide a comprehensive overview of the
current advances in managing and preventing progression of oral potentially malignant …

Background Proliferative verrucous leucoplakia (PVL) is a rare but slow-growing, aggressive
leucoplakia lesion associated with the highest malignant transformation rate in oral …

Oral leukoplakia (OLK) is the most emblematic oral potentially malignant disorder that may
precede the diagnosis of oral squamous cell carcinoma (OSCC) and has an overall …

Head and neck squamous cell carcinoma (HNSCC) is a spectrum of heterogeneous
malignancies. A variety of genetic, environmental, and lifestyle factors contribute to the …