After several decades, therapeutic cancer vaccines now show signs of efficacy and potential
to help patients resistant to other standard-of-care immunotherapies, but they have yet to …

With the development and regulatory approval of immune checkpoint inhibitors and adoptive
cell therapies, cancer immunotherapy has undergone a profound transformation over the …

Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results …

Ipilimumab, a monoclonal antibody against cytotoxic T lymphocyte antigen 4 (CTLA-4), has
been shown to improve survival in patients with advanced metastatic melanoma. It also …

Dendritic cells (DCs) are versatile elements of the immune system and are best known for
their unparalleled ability to initiate and modulate adaptive immune responses. During the …

Chimeric antigen receptor T cell (CAR T cell) therapy is a revolutionary approach approved
by the FDA and EMA to treat B cell malignancies and multiple myeloma. The production of …

Over the past two decades, gene therapy has garnered tremendous attention and is
heralded by many as the ultimate cure to treat diseases such as cancer, viral infections, and …

Within the last decade, the introduction of checkpoint inhibitors proposed to boost the
patients' anti-tumor immune response has proven the efficacy of immunotherapeutic …

Gene therapy is expected to treat various incurable diseases including viral infections,
autoimmune disorders, and cancers. Cationic lipids (CL) have been used as carriers of …

Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …