During epithelial tissue development, repair, and homeostasis, adherens junctions (AJs)
ensure intercellular adhesion and tissue integrity while allowing for cell and tissue …

Mechanobiology is an emerging field at the interface of biology and mechanics,
investigating the roles of mechanical forces within biomolecules, organelles, cells, and …

Animal development entails the organization of specific cell types in space and time, and
spatial patterns must form in a robust manner. In the zebrafish spinal cord, neural …

With five decades of sustained application, micropipette aspiration has enabled a wide
range of biomechanical studies in the field of cell mechanics. Here, we provide an update on …

Upon implantation, mammalian embryos undergo major morphogenesis and key
developmental processes such as body axis specification and gastrulation. However, limited …

Over the past decades, increasing evidence has indicated that mechanical loads can
regulate the morphogenesis, proliferation, migration, and apoptosis of living cells …

Cell and tissue mechanical properties are paramount in controlling morphogenesis.
Microaspiration techniques allow measuring the absolute values of mechanical properties in …

Cytotoxic T lymphocytes (CTLs) lyse target cells by delivering lytic granules that contain the
pore former perforin to the cytotoxic immunological synapse. Here, we establish that …

Cells shield organelles and the cytosol via an active boundary predominantly made of
phospholipids and membrane proteins, yet allowing communication between the …

Measuring forces from the piconewton to millinewton range is of great importance for the
study of living systems from a biophysical perspective. The use of flexible micropipettes as …