PIWI-interacting RNAs: small RNAs with big functions
In animals, PIWI-interacting RNAs (piRNAs) of 21–35 nucleotides in length silence
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
PIWI-interacting RNA: its biogenesis and functions
YW Iwasaki, MC Siomi, H Siomi - Annual review of biochemistry, 2015 - annualreviews.org
PIWI-interacting RNAs (piRNAs) are a class of small RNAs that are 24–31 nucleotides in
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
[HTML][HTML] Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles
Cells chemically isolate molecules in compartments to both facilitate and regulate their
interactions. In addition to membrane-encapsulated compartments, cells can form …
interactions. In addition to membrane-encapsulated compartments, cells can form …
Protein arginine methyltransferases and cancer
Y Yang, MT Bedford - Nature Reviews Cancer, 2013 - nature.com
There are nine protein arginine methyltransferases (PRMTs) encoded in mammalian
genomes, the protein products of which catalyse three types of arginine methylation …
genomes, the protein products of which catalyse three types of arginine methylation …
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
JA Law, SE Jacobsen - Nature Reviews Genetics, 2010 - nature.com
Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …
processes, including gene and transposon silencing, imprinting and X chromosome …
PIWI-interacting small RNAs: the vanguard of genome defence
PIWI-interacting RNAs (piRNAs) are a distinct class of small non-coding RNAs that form the
piRNA-induced silencing complex (piRISC) in the germ line of many animal species. The …
piRNA-induced silencing complex (piRISC) in the germ line of many animal species. The …
Post-translational modifications in signal integration
YL Deribe, T Pawson, I Dikic - Nature structural & molecular biology, 2010 - nature.com
Post-translational modifications of proteins and the domains that recognize these
modifications have central roles in creating a highly dynamic relay system that reads and …
modifications have central roles in creating a highly dynamic relay system that reads and …
Regulation and function of DNA methylation in plants and animals
DNA methylation is an important epigenetic mark involved in diverse biological processes.
In plants, DNA methylation can be established through the RNA-directed DNA methylation …
In plants, DNA methylation can be established through the RNA-directed DNA methylation …
An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes
Animal germ cells produce PIWI-interacting RNAs (piRNAs), small silencing RNAs that
suppress transposons and enable gamete maturation. Mammalian transposon-silencing …
suppress transposons and enable gamete maturation. Mammalian transposon-silencing …
A single mechanism of biogenesis, initiated and directed by PIWI proteins, explains piRNA production in most animals
In animals, PIWI-interacting RNAs (piRNAs) guide PIWI proteins to silence transposons and
regulate gene expression. The mechanisms for making piRNAs have been proposed to …
regulate gene expression. The mechanisms for making piRNAs have been proposed to …