Pathophysiology of Takotsubo Syndrome: JACC State-of-the-Art Review

AR Lyon, R Citro, B Schneider, O Morel… - Journal of the American …, 2021 - jacc.org
Takotsubo syndrome (TTS) has been a recognized clinical entity for 31 years, since its first
description in 1990. TTS is now routinely diagnosed in patients who present with acute chest …

A synopsis on aging—Theories, mechanisms and future prospects

JP da Costa, R Vitorino, GM Silva, C Vogel… - Ageing research …, 2016 - Elsevier
Answering the question as to why we age is tantamount to answering the question of what is
life itself. There are countless theories as to why and how we age, but, until recently, the very …

International expert consensus document on Takotsubo syndrome (part I): clinical characteristics, diagnostic criteria, and pathophysiology

JR Ghadri, IS Wittstein, A Prasad… - European heart …, 2018 - academic.oup.com
Takotsubo syndrome (TTS) is a poorly recognized heart disease that was initially regarded
as a benign condition. Recently, it has been shown that TTS may be associated with severe …

Pathophysiology of T akotsubo syndrome–a joint scientific statement from the Heart Failure Association T akotsubo Syndrome Study Group and Myocardial Function …

E Omerovic, R Citro, E Bossone… - European journal of …, 2022 - Wiley Online Library
This is the first part of a scientific statement from the Heart Failure Association (HFA) of the
European Society of Cardiology focused upon the pathophysiology of Takotsubo syndrome …

Biological and functional biomarkers of aging: definition, characteristics, and how they can impact everyday cancer treatment

G Colloca, B Di Capua, A Bellieni, D Fusco… - Current Oncology …, 2020 - Springer
Abstract Purpose of Review Recognize which are the elements that predict why a person is
aging faster or slower and which intervention we can arrange to slow down the process …

Metabolic alterations in a rat model of takotsubo syndrome

N Godsman, M Kohlhaas, A Nickel… - Cardiovascular …, 2022 - academic.oup.com
Aims Cardiac energetic impairment is a major finding in takotsubo patients. We investigate
specific metabolic adaptations to direct future therapies. Methods and results An …

Current knowledge and future challenges in Takotsubo syndrome: part 1—pathophysiology and diagnosis

E Rawish, T Stiermaier, F Santoro, ND Brunetti… - Journal of clinical …, 2021 - mdpi.com
First recognized in 1990, takotsubo syndrome (TTS) constitutes an acute cardiac condition
that mimics acute myocardial infarction commonly in the absence of obstructive coronary …

Molecular mechanisms of takotsubo syndrome

LS Couch, K Channon, T Thum - International Journal of Molecular …, 2022 - mdpi.com
Takotsubo syndrome (TTS) is a severe but reversible acute heart failure syndrome that
occurs following high catecholaminergic stress. TTS patients are similar to those with acute …

The immunology of takotsubo syndrome

KRQ Lim, DL Mann, T Kenzaka, T Hayashi - Frontiers in immunology, 2023 - frontiersin.org
Takotsubo syndrome (TTS) is a disorder characterized by transient cardiac dysfunction with
ventricular regional wall motion abnormalities, primarily thought to be caused by the effects …

Nitrosative stress as a modulator of inflammatory change in a model of Takotsubo syndrome

SY Surikow, TH Nguyen, I Stafford, M Chapman… - JACC: Basic to …, 2018 - jacc.org
Previous studies have shown that patients with Takotsubo syndrome (TS) have supranormal
nitric oxide signaling, and post-mortem studies of TS heart samples revealed nitrosative …