The potential for ischemic preconditioning to reduce infarct size was first recognized more
than 30 years ago [180]. Despite extension of the concept to ischemic postcondition‑ing …

Heart diseases due to myocardial ischemia, such as myocardial infarction or ischemic heart
failure, are major causes of death in developed countries, and their number is unfortunately …

Ischaemic postconditioning (brief periods of ischaemia alternating with brief periods of
reflow applied at the onset of reperfusion following sustained ischaemia) effectively reduces …

A series of brief (a few minutes) ischemia/reperfusion cycles (ischemic preconditioning, IP)
limits myocardial injury produced by a subsequent prolonged period of coronary artery …

Reperfusion therapy is the indispensable treatment of acute myocardial infarction (AMI) and
must be applied as soon as possible to attenuate the ischemic insult. However, reperfusion …

Ischemic postconditioning, a simple mechanical maneuver at the onset of reperfusion,
reduces infarct size after ischemia/reperfusion. After its first description in 2003 by Zhao et al …

Following a period of ischemia (local restriction of blood supply to a tissue), the restoration of
blood supply to the affected area causes significant tissue damage. This is known as …

Translation of cardioprotective interventions aimed at reducing myocardial injury during
ischaemia–reperfusion from experimental studies to clinical practice is an important yet …

Postconditioning (PostC), or relief of myocardial ischemia in a stuttered manner, has been
shown to reduce infarct size, due in part to upregulation of survival kinase signaling. Virtually …

Post-ischemic reperfusion may result in reactive oxygen species (ROS) generation, reduced
availability of nitric oxide (NO•), Ca2+ overload, prolonged opening of mitochondrial …