Tumor–stroma interactions have emerged as critical determinants of drug efficacy. However,
the underlying biological and physicochemical mechanisms by which the microenvironment …

Over the past two decades, quantitative proteomics has emerged as an important tool for
deciphering the complex molecular events involved in cancers. The number of references …

Background and Aims Advances in cross-sectional imaging have resulted in increased
detection of intraductal papillary mucinous neoplasms (IPMNs), and their management …

Pancreatic cancer (PaCa) has a dismal prognosis and adjuvant immunotherapy frequently is
of low efficacy due to immunosuppressive features of PaCa and PaCa-stroma. We here …

Background: Pancreatic cancer is one of the malignant tumors that threaten human health.
Methods: The gene expression profiles of GSE15471, GSE19650, GSE32676 and …

Angiogenesis is a universal requirement for the growth of solid tumours beyond the limits of
oxygen diffusion from the existing vasculature. The expression and function of …

Recent years have seen a considerable emphasis on growth factors and the elucidation of
their mode of function, which has led to the recognition that growth factors, their receptors as …

Intraductal oncocytic papillary neoplasm (IOPN) of the pancreas is a recently recognized
pancreatic tumor. Here, we aimed to determine the most essential features with the …

Pancreatic cancer is one of the most lethal malignancies, with a prominent desmoplastic
reaction as its defining hallmark. The past several decades have seen dramatic progress in …

Purpose Nectin-1 is a cell adhesion molecule that regulates the formation of adherens
junctions and tight junctions. We measured the expression of nectin-1 in cancer-associated …