Ion channels and signaling in the pituitary gland

SS Stojilkovic, J Tabak, R Bertram - Endocrine reviews, 2010 - academic.oup.com
Endocrine pituitary cells are neuronlike; they express numerous voltage-gated sodium,
calcium, potassium, and chloride channels and fire action potentials spontaneously …

Smoking, nicotine and neuropsychiatric disorders

P Dome, J Lazary, MP Kalapos, Z Rihmer - Neuroscience & Biobehavioral …, 2010 - Elsevier
Tobacco smoking is an extremely addictive and harmful form of nicotine (NIC) consumption,
but unfortunately also the most prevalent. Although disproportionately high frequencies of …

[HTML][HTML] Nicotinic cholinergic system and COVID-19: in silico identification of an interaction between SARS-CoV-2 and nicotinic receptors with potential therapeutic …

K Farsalinos, E Eliopoulos, DD Leonidas… - International journal of …, 2020 - mdpi.com
While SARS-CoV-2 uses angiotensin converting enzyme 2 (ACE2) as the receptor for cell
entry, it is important to examine other potential interactions between the virus and other cell …

[HTML][HTML] Structure and function meet at the nicotinic acetylcholine receptor-lipid interface

FJ Barrantes - Pharmacological Research, 2023 - Elsevier
The nicotinic acetylcholine receptor (nAChR) is a transmembrane protein that mediates fast
intercellular communication in response to the endogenous neurotransmitter acetylcholine …

Alpha5 nicotinic acetylcholine receptor mediates nicotine-induced HIF-1α and VEGF expression in non-small cell lung cancer

X Ma, Y Jia, S Zu, R Li, Y Jia, Y Zhao, D Xiao… - Toxicology and applied …, 2014 - Elsevier
By binding to nicotinic acetylcholine receptors (nAChRs), nicotine induces the proliferation
and apoptosis of non-small cell lung cancer (NSCLC). Previous studies have indicated that …

α5-nAChR modulates nicotine-induced cell migration and invasion in A549 lung cancer cells

H Sun, X Ma - Experimental and Toxicologic Pathology, 2015 - Elsevier
Cigarette smoking is the most important risk factor in the development of human lung cancer.
Nicotine, the major component in tobacco, not only contributes to carcinogenesis but also …

[HTML][HTML] Ion channels of pituitary gonadotrophs and their roles in signaling and secretion

SS Stojilkovic, I Bjelobaba, H Zemkova - Frontiers in endocrinology, 2017 - frontiersin.org
Gonadotrophs are basophilic cells of the anterior pituitary gland specialized to secrete
gonadotropins in response to elevation in intracellular calcium concentration. These cells …

MmTX1 and MmTX2 from coral snake venom potently modulate GABA (A) receptor activity

JP Rosso, JR Schwarz, M Diaz-Bustamante, B Céard… - Biophysical …, 2015 - cell.com
GABA (A) receptors shape synaptic transmission by modulating Cl-conductance across the
cell membrane. Remarkably, animal toxins that target GABA (A) receptors have not yet been …

[HTML][HTML] Revisiting nicotine's role in the ageing brain and cognitive impairment

A Majdi, F Kamari, MS Vafaee… - Reviews in the …, 2017 - degruyter.com
Brain ageing is a complex process which in its pathologic form is associated with learning
and memory dysfunction or cognitive impairment. During ageing, changes in cholinergic …

[HTML][HTML] Understanding of nicotinic acetylcholine receptors

J Wu - Acta Pharmacologica Sinica, 2009 - nature.com
Cigarette smoking is a major public health problem and has been identified as the second-
most prevalent cause of death in the world. China, a country with a population of 1.3 billion …