[HTML][HTML] Natural products as reservoirs of novel therapeutic agents

S Mushtaq, BH Abbasi, B Uzair, R Abbasi - EXCLI journal, 2018 - ncbi.nlm.nih.gov
Since ancient times, natural products from plants, animals, microbial and marine sources
have been exploited for treatment of several diseases. The knowledge of our ancestors is …

The multiplicity of hairy root cultures: prolific possibilities

NN Ono, L Tian - Plant science, 2011 - Elsevier
Hairy root cultures (HRCs), induced by Agrobacterium rhizogenes infection, have been
established from a wide variety of plant species. HRCs accumulate phytochemicals to levels …

Hairy root cultures as a source of phenolic antioxidants: simple phenolics, phenolic acids, phenylethanoids, and hydroxycinnamates

J Malarz, YV Yudina, A Stojakowska - International Journal of Molecular …, 2023 - mdpi.com
Plant-derived antioxidants are intrinsic components of human diet and factors implicated in
tolerance mechanisms against environmental stresses in both plants and humans. They are …

Echinacea biotechnology: advances, commercialization and future considerations

JL Parsons, SI Cameron, CS Harris… - Pharmaceutical …, 2018 - Taylor & Francis
Context: Plants of the genus Echinacea (Asteraceae) are among the most popular herbal
supplements on the market today. Recent studies indicate there are potential new …

Gibberellic Acid Increases Secondary Metabolite Production in Echinacea purpurea Hairy Roots

BH Abbasi, AR Stiles, PK Saxena, CZ Liu - Applied biochemistry and …, 2012 - Springer
Gibberellic acid (GA 3) is reported to have diverse effects on hairy root cultures of many
plant species; therefore, the effects of GA 3 on the growth, secondary metabolite production …

Biotechnological production of caffeic acid derivatives from cell and organ cultures of Echinacea species

HN Murthy, YS Kim, SY Park, KY Paek - Applied microbiology and …, 2014 - Springer
Caffeic acid derivatives (CADs) are a group of bioactive compounds which are produced in
Echinacea species especially Echinacea purpurea, Echinacea angustifolia, and Echinacea …

Hairy root culture: bioreactor design and process intensification

AR Stiles, CZ Liu - Biotechnology of hairy root systems, 2013 - Springer
<? xm-replace_text {Heading}?> Abstract The cultivation of hairy roots for the production of
secondary metabolites offers numerous advantages; hairy roots have a fast growth rate, are …

Bioreactors for hairy roots culture: a review

SA Khan, MH Siddiqui, K Osama - Current Biotechnology, 2018 - ingentaconnect.com
Background: Plants are a source of a variety of secondary metabolites. Agrobacterium
rhizogenes mediated hairy root cultures offer a great advantage for the production of these …

Improving root growth and cichoric acid derivatives production in hairy root culture of Echinacea purpurea by ultrasound treatment

R Liu, W Li, LY Sun, CZ Liu - Biochemical engineering journal, 2012 - Elsevier
An efficient ultrasound-stimulation strategy was developed for improving the hairy root
growth and caffeic acid derivatives (CADs) biosynthesis in the hairy root cultures of …

The current status and future applications of hairy root cultures

N Dhiman, V Patial, A Bhattacharya - Biotechnological Approaches for …, 2018 - Springer
Hairy roots are produced when the soil phytopathogen, Agrobacterium rhizogenes, infects a
host plant. Just like normal roots, the hairy roots have the capacity to absorb target elements …