Microtubule-associated proteins (MAPs) were initially discovered as proteins that bind to
and stabilize microtubules. Today, an ever-growing number of MAPs reveals a more …

Neurons, the basic information processing units of the nervous system, are characterized by
a complex polar morphology which is essential for their function. To attain their precise …

Hyperphosphorylated microtubule-associated protein tau is the major component of the
paired helical filament of Alzheimer's disease. Phosphorylation-dependent anti-tau …

The microtubule cytoskeleton forms complex macromolecular assemblies with a range of
microtubule-associated proteins (MAPs) that have fundamental roles in cell architecture …

Abstract Microtubule associated protein 2 (MAP‐2) historically has been perceived primarily
as a static, structural protein, necessary along with other cytoskeletal proteins to maintain …

The active zone is a specialized region of the presynaptic plasma membrane where synaptic
vesicles dock and fuse. In this study, we have investigated the cellular mechanism …

Tau and MAP2 are two of the major microtubuleassociated proteins in the vertebrate
nervous system. They promote microtubule assembly and stability, and might be involved in …

Microtubule-associated proteins (MAPs) function to regulate the assembly dynamics and
organization of microtubule polymers. Upstream regulation of MAP activities is the major …

Microtubules are flexible polymers whose mechanical properties are an important factor in
the determination of cell architecture and function. It has been proposed that the two most …

The phosphorylation of microtubule-associated proteins (MAPs) is thought to be a key factor
in the regulation of microtubule stability. We have shown recently that a novel protein kinase …