A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis
AK Alexander, EJ Rice, J Lujic, LE Simon… - Nature …, 2023 - nature.com
During meiotic prophase I, spermatocytes must balance transcriptional activation with
homologous recombination and chromosome synapsis, biological processes requiring …
homologous recombination and chromosome synapsis, biological processes requiring …
Casting histone variants during mammalian reproduction
G Karam, A Molaro - Chromosoma, 2023 - Springer
During mammalian reproduction, germ cell chromatin packaging is key to prepare parental
genomes for fertilization and to initiate embryonic development. While chromatin …
genomes for fertilization and to initiate embryonic development. While chromatin …
Heterogeneity in the epigenetic landscape of murine testis-specific histone variants TH2A and TH2B sharing the same bi-directional promoter
I Singh, P Parte - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Testis-specific histone variants are crucial to promote open chromatin structure to enable
nucleosome disassembly in the final stages of spermiogenesis. However, even after histone …
nucleosome disassembly in the final stages of spermiogenesis. However, even after histone …
5-methylcytidine effectively improves spermatogenesis recovery in busulfan-induced oligoasthenospermia mice
C Wang, T Ye, J Bao, J Dong, W Wang, C Li… - European Journal of …, 2024 - Elsevier
The function and regulatory mechanisms of 5-methylcytidine (m 5 C) in oligoasthenospermia
remain unclear. In this study, we made a mouse model of oligoasthenospermia through the …
remain unclear. In this study, we made a mouse model of oligoasthenospermia through the …
Meiotic gene transcription programs are mediated by A-MYB and BRDT-dependent RNA polymerase II pause release during mammalian prophase I
During meiotic prophase I, germ cells must balance transcriptional activation with meiotic
recombination and chromosome synapsis, biological processes requiring extensive …
recombination and chromosome synapsis, biological processes requiring extensive …
精子变形过程中组蛋白-鱼精蛋白替换调控机制
袁露， 葛婷婷， 牛长敏， 徐文华， 郑英 - 遗传, 2021 - chinagene.cn
精子形成是精子发生的最后阶段, 圆形精子细胞经历了一系列的形态变化和染色质凝聚,
形成了具有物种特异性的成熟精子. 组蛋白-鱼精蛋白替换是精子形成过程中的重要事件 …
形成了具有物种特异性的成熟精子. 组蛋白-鱼精蛋白替换是精子形成过程中的重要事件 …